BETA LACTAMS Flashcards
1
Q
major production of this is the major mech of resistance to beta lactams?
A
beta lactamase
2
Q
if chromosomal, resistance against? plasma mediated?
A
entire species
particular strain
3
Q
what are the ext4ended spectrum beta lactamases?
A
TEM
SHV
CTX-M
4
Q
hydrolyzes penicillins and cephalosporins
CTX-M, SHV, TEM, KPC
E Coli, Klebsiella, Enterobacteriacese, Pseudomonas
A
Penicillinases, ESBLs, carbapenmases
5
Q
uses zinc for hydrolysis of beta lactam ring
IMP, NDM***,VIM
pseudomonas, acinetobacter
A
metallo-beta-lactamases
6
Q
hydrolysis broad and extended spectrum cephalosporins
amp c
enterobacter, citrobacter proteus
A
cephalosporins
7
Q
beta lactamase production and reduced permeability or increased efflux
OKA
acinetobacter, E. coli, pseudomonas
A
oxacillinases
