AMIODORONE Flashcards
1
Q
amiodarone is what class drug?
A
class III potassium channel blocker
2
Q
notable characteristic of amiodarone?
A
most effective antiarrhythmic action
3
Q
this class III drug increases the refractory period, but this drug and sotalol decreases AV nodal conduction?
A
amiodarone
4
Q
major side effects of amiodarone?
A
has a wide range body of distribution, except kidney pulmonary toxicity thyroid toxicity hepatoxicity cardiac toxicity Neurologic ocular(corneal deposits) GI (N/V)
5
Q
Amiodarone incidence of fatality?
A
10% fatalities
6
Q
amiodarone inhibits what enzyme?
A
CYP3A4, so cisapride, theophylline, statins
7
Q
digoxin levels
warfarin effects
procainamide levels
these are increased or decreased by amiodarone?
A
increased
8
Q
the drug interactions, specifically the pharmacodynamics affects what meds?
A
calcium channel blockers
beta blockers
