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Flashcards in Psychiatry Deck (172)
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91

What are the main side effects of high potentcy neuroleptics?

EPS symptoms

92

What are the main side effects of low potentcy neuroleptics?

anti-cholineric

anti-α1

anti-histaminergic

93

Do typical antipsychotics treat the positive or negative effects?

positive

94

Are neuroleptics fat or water soluble?

fat

95

What two drugs are used to treat the EPS side effects of neuroleptics?

benztropine

diphenhydramine

96

Where does chlorpromazine deposit?

cornea

97

Where does thioridazine deposit?

retina

98

What is the time frame for bradykinesia regarding neuroleptic use?

four weeks

99

What is the time frame for tardive dyskinesia regarding neuroleptic use?

four months

100

What could be found in the urine during NMS?

myoglobin

101

What are the six atypical antipsychotics?

Olanzapine

Clonazpine

Quietapine

Risperidone

Aripiprazole

Ziprasidone

102

Which symptoms of schizophrenia do atypicals treat?

positive and negative

103

Which two atypical anti-psychotics can cause weight gain?

clonzapine and olanzapine

104

Which atypical antipsychotic can cause agranulocytosis?

Clozapine

105

Which atypical antipsychotic can prolong QT?

Ziprasidone

106

Which atypical is used for severe, refractory Schizophrenia?

Clozapine

107

What is the proposed mechanism of lithium?

inhibit phosphoinositol pathway

108

What hormone does lithium antagonize?

ADH

109

What does lithium do to the heart rate?

heart block

110

What two heart defects does lithium cause?

Ebsteins

Transposition

111

What part of the nephron reabsorbs lithium?

PCT

112

What ion does lithium follow?

sodium

113

Which receptor does buspirone work at? Antagonize or agonize?

5HT-1A

agonize

114

What is the one drawback of buspirone?

takes 1-2 weeks to work

115

Which receptor does mirtazapine work on? Antagonize or agonize?

α2

antagonize

116

What are the four SSRIs?

Fluoxetine

Paroxetine

Citalopram

Sertraline

117

How many weeks does it take SSRIs to begin to function?

4-8 weeks

118

Which receptor does cyproheptadine antagonize?

5HT2

119

Does NMS present with muscle rigidity or shivering?

rigidity

120

Does serotonin syndrome present with muscle rigidity or shivering?

shivering