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Flashcards in Endocrine Deck (254)
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1

What is the remnant of the thyroglossal duct?

Foramen Cecum

2

How does thyroglossal duct cyst present?

anterior midline neck mass that moves

3

What tracer can be used to identify a thyroglossal duct cyst?

technitium-99

4

What is the most common tumor of adrenal medulla in children?

Neuroblastoma

5

Does a neuroblastoma cause hypertension?

rarely

6

How do the left and right adrenal glands drain?

just like gonadal veins

7

What does neurophysin I carry?

Oxytocin

8

What does neurophysin two carry?

ADH

9

What does the posterior pituitary develop from?

Neuroectoderm

10

What are the two acidophilic anterior pituitary hormones?

GH and prolactin

11

What are the four basophilic anterior pituitary hormones?

FSH/LH/ACTH/TSH

12

What embryological layer is the anterior pituitary derived from? Also known as?

ectoderm

Rathke's Pouch

13

Which four hormones share similar α subunits?

FSH/LH/TSH/βHCG

14

Where in the α-cells is glucagon stored?

peripherally

15

Where in the β-cells is insulin stored?

centrally

16

Where in the Δ-cells is somatostatin stored?

interspersed

17

What is the function of 11β-HSD?

cortisol into cortisone or vice-versa

18

Which isoform of 11β-HSD is found in aldosterone sensitive tissues?

11β-HSD2

19

What compound is found in licorice? Also known as?

Glycyrrhetic acid

enoxolone

20

What enzyme can glycyrrhetic acid/enoxolone inhibit? What does this lead to?

11β-HSD2

syndrome of apparent mineralocorticoid excess

21

In what ratio are insulin and C-peptide released together?

equally

22

What type of activity do insulin receptors possess?

tyrosine kinase

23

What does insulin do to sodium levels?

sodium retention

24

Does insulin cross the placenta?

no

25

Which GLUT receptor is present on β-cells?

GLUT2

26

In which three tissues are GLUT1 found?

RBCs/Brain/Cornea

27

Which six tissues take-up glucose independent of insulin?

Brain/RBCs/Intestine/Cornea/Kidneys/Liver

28

What does Growth Hormone due to insulin release?

increase

29

What do β2 Agonists do to insulin release?

increase

30

What would a prolactinoma do to bones?

Osteoporosis