Flashcards in Heme and Onc. Deck (501)
What cell type contains dense granules? What are the two products of dense granules?
ADP and calcium
What type of cell contains αgranules? What are the two products of αgranules?
vWF and fibrinogen
In what organ is approximately 1/3 of platelet pool stored?
What is the vWF receptor?
What is the fibrinogen receptor?
What four enzymes are contained by neutrophils?
Do macrophages function via MHC II or MHC I?
What type of nucleus do eosinophils possess?
What two enzymes are produced by eosinophils granules?
histaminase and arylsulfatase
What are the three components of basophil granules?
histamine, heparin and leukotrienes
What form of leukemia can isolated basophilia be indicative of?
What granulocyte binds Fc of IgE?
What drug prevents mast cell degranulation?
What two receptors do dendritic cells express?
Fc and MHC II
What are dendritic cells in the skin called?
What two CD molecules are expressed by B-lymphocytes?
19 and 20
What is the CD molecule required for T-cell activation?
Multiple myeloma is a cancer of what cell type?
If a person has type A blood, What antigen do they express on RBCs? What antibody is circulating?
A = RBC
Anti-B = circulating
If a person has type B blood, What antigen do they express on RBCs? What antibody is circulating?
B = RBC
anti-A = circulating
What type of immunoglobulin targets RBC antigens?
anti-Rh is what type of antibody?
If a person has type AB blood, What antigen do they express on RBCs? What antibody is circulating?
A and B = RBC
no circulating antibodies
What can people with AB blood universally donate?
What can people with AB blood universally receive?
If a person has type O blood, What antigen do they express on RBCs? What antibody is circulating?
no antigen on RBCs
antigens to A and B in plasma
What can people with O blood universally donate?
What can people with type O blood universally accept?
What three coagulation factors can thrombin activate?
V and VIII and thirteen