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Flashcards in Reproductive Deck (377)
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1

What is the function of sonic hedge hog gene?

patterning along anterior/posterior axis

2

What can a mutation in sonic hedgehog cause?

holoprosencephaly

3

What is the function of Wnt?

organization along the dorsal-ventral axis

4

What is the function of homeobox genes? What do Hox mutations produce?

craniocaudal organization

limbs in the wrong location

5

What happens within one week?

implantation of blastocyst and

6

When does the bilaminar disk for?

2 weeks

7

What happens within three weeks? What is this called?

formation of trilaminar disk

gastrulation

8

Between what two weeks is the embryo most susceptible to teratogens?

3-8 weeks

9

At what week does the heart begin to beat?

four weeks

10

At what week are all four limbs developed?

week four

11

At what week can a fetal heart be seen?

week 6

12

At what week are genitalia visible?

week 10

13

What starts gastrulation?

epiblast invaginating to form primitive streak

14

What is Rathke's pouch?

depression in the roof of the mouth

15

What does Rathke's pouch develop into?

anterior pituitary

16

What is another name for the pituitary? Which embryological layer?

adenohypophysis

surface ectoderm

17

What is a really easy way to remember what the neuroectoderm is?

CNS

18

What is a really easy way to remember what the neural crest is?

PNS

19

Is deformation an extrinsic or intrinsic process? When does a deformation occur?

extrinsic

after embryonic period

20

Is malformation an extrinsic or intrinsic process? When does it occur?

intrinsic

during embryonic period

21

What is a sequence?

abnormalities arising from a single embryological event

22

What kind of birth defects do ACE inhibitors cause?

renal

23

What kind of birth defects do alkylating agents cause?

absence of digits

24

What kind of birth defects does carbamazepine cause?

neural tube defects

25

What kind of birth defects does DES cause?

vaginal clear cell carcinoma

26

What kind of birth defects do folate antagonists cause?

neural tube defects

27

What kind of birth defects does lithium cause?

Ebstein anamoly

28

What birth defect does methimazole cause?

Aplasia cutis congenita

29

What kind of birth defects do tetracyclines cause?

discolored teeth

30

What type of birth defects would folate cause?

neural tube defects