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Flashcards in Renal Deck (377)
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1

What week does the Pronephros degenerate?

4th week

2

What trimester does the mesonephros function as an interim kidney? Does the mesonephros contribute to the male or female reproductive system?

1st trimester

male

3

In what week does the mesonephros develop?

5th week

4

What week does nephrogenesis finish?

36th week

5

What duct is the Ureteric bud developed from?

Mesonephric duct

6

From what structure to what structure does the Ureteric bud develop into in the adult kidney?

from the collecting duct to the ureter

7

By what week is the ureteric bud fully canalized?

10th week

8

The metanephric mesenchyme is responsible for the development of from where to where in the adult kidney?

glomerulus to DCT

9

What structure is the most likely to become obstructed during development? Why?

uretopelvic junction

last to canalize

10

What are the three causes of Potter Syndrome?

ARPKD

Bilateral renal artery agenesis

posterior urethral valves

11

What is the O of POTTER Sequence?

Oligohydramnios

12

What is amnion nodosum? What type of epithelium?

nodules on the amnion

squamous

13

The association of what two structures is defective during Multicystic Dysplastic Kidney?

metanephric mesenchyme

ureteric bud

14

What two components fill the kidney during dysplastic kidney?

cysts and cartilage

15

Is dysplastic more common in a bilateral or unilateral pattern?

unilateral

16

Do the ureters pass under or over the uterine artery?

under

17

Do the ureters pass under or over the ductus deferens?

under

18

Does creatinine over-estimate or under-estimate GFR? Why?

over-estimate

small amount of creatinine is secreted

19

What equation is used to estimate RPF?

PAH clearance

20

What is the equation for Filtration Fraction?

GFR/RPF

21

Does low plasma protein increase or decrease the GFR?

increase

22

What is the normal osmolality of ECF?

290 mOsm/L

23

What is the equation for filtered load?

(GFR)([Plasma])

24

At what blood glucose concentration does glucosuria begin to happen?

200 mg/dL

25

At what blood glucose concentration do PCT transporters begin to be saturated?

375 mg/dL

26

What two metabolites begin to accumulate in the urine during pregnancy?

glucose and amino acids

27

What is the mode of inheritance for Hartnup Disease?

autosomal recessive

28

Which amino acid specifically is underabsorbed during Hartnup Disease?

tryptophan

29

What are the two locations of defective transporters during Hartnup Disease?

PCT ad enterocytes

30

Which disease does Hartnup disease mimmic?

pellagra