Flashcards in Biochemistry Deck (372)
What ribosomes make up the eukaryotic ribosome?
40S and 60S
What ribosomes make up the prokaryotic ribosome?
30S and 50S
What is the energy source for the intitiation of protein synthesis?
What does the A site of the ribosome hold?
A-mino acyl tRNA
What amino acid charged tRNA does not bind to the A site?
What is the function of rRNA?
catalyze peptide bond
What does 'A' of APE stand for according to translation?
accodomates incoming amino-acyl tRNA
What does 'P' of APE stand for according to translation?
acomodates growing Peptide
What does 'E' of APE stand for according to translation?
holds Empty tRNA
What are the three stop codons?
UAG, UAA, UGA
What are the two stable (quiescent) cell types?
hepatocytes and lymphocytes
What organelle do Nissl bodies function as?
What cell type are Nissl bodies found in?
What two activities occur at the smooth ER?
N-linked glycosylation occurs on what amino acid?
O-linked glycosylation occurs on what amino acid?
serine and threonine
What monosaccharide is added to proteins for them to be trafficked to what organelle?
What is defective in I-cell disease? Which organelle is responsible for the error?
phosphorylation of mannose residues
Does COP-I traffic anterograde or retrograde?
Does COP-II traffic anterograde or retrograde?
What two types of fatty acids are processed in the peroxisome?
very long chain and branched chain
What heterodimer makes up microtubules? What molecule do microtubules use for energy?
α-tubulin and β-tubulin
What three structures possess microtubules?
flagella, cilia and mitotic spindles
What five drugs act on microtubules?
Mebendazole,Griseofulvin, Colchicine, Vincristine/Vinblastine, Paclitaxel
What is the mnenomic for the five drugs that act on microtubules?
Microtubules Get Constructed Very Poorly
Is dynein retrograde or anterograde?
Is kinesis retrograde or anterograde?
Do cilic have a 9+2 or a 9+3 arrangement?
What structure is defective in kartagener syndrome? What specific protein?