Antibody Function and Complement Flashcards
Humoral immunity refers to ________.
antibody-mediated immunity
Epitopes are usually _______.
ten to twenty amino acids long
The first immunoglobulin to be present in blood after an infection is ____, but later ____ is found in greater concentrations.
IgM; IgG
____ is the only antibody that the human fetus makes.
IgM
There are about _______ of IgG in the blood.
1,000 mg/dL
The plasma half-life of IgG is _____.
three weeks
IgE combats _____ and is involved in _______ reactions.
parasites; allergic
The alternative pathway (of complement activation) works by ____________.
activating C3 with molecules on the microbe’s surface, thus activating C5 without needing antibody, C1, C4, or C2
Haptens are __________.
small molecules that elicit immunologic response
IgM is best at _______.
activating complement
IgG is best at _________.
activating phagocytosis (opsonization)
Secretory component keeps ___ from being degraded and comes from the ________.
IgA; receptor in epithelial cells that pumps IgA into mucous membranes
The classical pathway (of complement activation) is stimulated by ______.
IgG and IgM
Uticaria are ______.
“giant” hives
The classical pathway is regulated mainly by ________.
C1 esterase inhibitor
