Anatomy and Physiology of the Immune System Flashcards

1
Q

In the nervous system, macrophages are called _______.

A

microglia

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2
Q

“Mononuclear cells” refers to ______ and _____, because their nuclei are simpler than granulocytes.

A

monocytes; lymphocytes

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3
Q

Eosinophils fight _______.

A

parasites

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4
Q

Describe the anatomy of a lymph node.

A

The outermost layer is cortex, then deep cortex (or paracortex), and finally medulla. There are afferent and efferent lymphatics and blood vessels.

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5
Q

Where in the lymph node are antibodies made?

A

Cortex

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6
Q

T cells reside in the _____.

A

Paracortex / deep cortex

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7
Q

Lymph nodes in the wall of the intestine are called ______.

A

Peyer patches

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8
Q

The “buffy coat” in centrifuged blood is _______.

A

leukocytes

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9
Q

Polymorphonuclear cells are _______.

A

cells whose nuclei are lobular (i.e., granulocytes)

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10
Q

List the leukocytes in order of most to least populous.

A

Neutrophils > lymphocytes > monocytes > eosinophils > basophils (although young children have more lymphocytes than neutrophils)

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11
Q

Of lymphocytes, what percent are T and B?

A

70% T, 20% B, 10% other

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12
Q

Central lymphoid organs are organs in which _______.

A

lymphocytes develop

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13
Q

Peripheral lymphoid organs include ________.

A

Peyer patches, lymph nodes, the spleen, lymph vessels, tonsils, adenoids

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14
Q

Lymph enters in the _________ and exits through ______.

A

subscapular sinus; efferent lymphatics (at the hilum)

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15
Q

Which is denser, the cortex or the paracortex?

A

The cortex

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16
Q

Postcapillary venule cells are ________.

A

high and cuboidal

17
Q

When a lymphocyte extravasates at a lymph node, it drains into ________.

A

lymph ducts that take it to the next lymph node and then finally the venous circulation (via the cisterna chylii)

18
Q

Red pulp (in the spleen) corresponds to _____.

A

the medulla of the lymph nodes (where filtration takes place)

19
Q

Peyer patches drain into _______.

A

the mesenteric lymph nodes

20
Q

Activated T and B cells are confusingly referred to as ________.

A

T lymphoblasts and B lymphoblasts