Drug Therapy to Suppress Immunity Ch 11 Flashcards Preview

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Flashcards in Drug Therapy to Suppress Immunity Ch 11 Deck (9)
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1

Autoantigens

protein complexes on a person's own tissue that stimulate an abnormal immune reaction

2

Autoimmune disorders

conditions associated with an abnormal immune response to self-antigens (autoantigens) on body tissue, resulting in ongoing inflammation and damage to body tissues

3

Cytotoxic

causing cell death

4

Graft rejection reaction

activated immunological response by the recipient to graft donor organ cells resulting in graft tissue damage and loss of graft organ function

5

Graft-versus-host disease

complication of bone marrow or stem cell transportation where activated T cells in donor bone marrow attack host tissues producing inflammatory changes in the skin, liver, and gastrointestinal tract, also can occur infrequently with a blood transfusion

6

Immunosuppression

suppression of the immune system

7

Monoclonal antibody

immunoglobulin therapeutically replicated in laboratory cells to react with a specific cell antigen altering the immune response to that antigen

8

Murine antibodies

immunoglobulins created in mouse cells for use as therapeutic treatment for human diseases

9

Polyclonal antibody

mixtures of antibodies (IgA, IgD, IgE, IgG, and IgM) produced by several clones of B lymphocytes