Drug Therapy with Corticosteroids Ch 15 Flashcards Preview

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Flashcards in Drug Therapy with Corticosteroids Ch 15 Deck (11)
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1

Addison’s disease

primary adrenocortical insufficiency with inadequate production of cortisol and aldosterone

2

Addisonian crisis

condition that mimics hypovolemic and septic shock; also known as adrenocortical insufficiency

3

Aldosterone

mineralocorticoid hormone secreted by the adrenal cortex to increase sodium reabsorption by the kidneys and indirectly regulate blood levels of potassium, sodium, and bicarbonate; also regulates pH, blood volume, and blood pressure

4

Corticosteroid

steroid hormones produced by the adrenal cortex; examples include androgens, glucocorticoids, and mineralocorticoids

5

Cortisol

the main glucocorticoid secreted as part of the body’s response to stress

6

Cushing’s disease

adrenocortical hyperfunction; may result from excessive corticotropin or primary adrenal tumor

7

Glucocorticoid

adrenal cortical hormone that protects the body against stress and affects protein and carbohydrate metabolism

8

Immunosuppression

suppression of the immune system

9

Mineralocorticoid

steroid hormone released by the adrenal cortex to promote sodium and water retention and potassium excretion

10

Negative feedback mechanism

when the output of a system affects the stimulus for the system (e.g., hormone secretion produces an effect that shuts off the stimulus for further hormone secretion)

11

Steroid

lipid-soluble hormone produced by the gonadal organs or the adrenal cortex