Drug Therapy With Macrolides, Ketolides, and Miscellaneous Anti-Infective Agents CH 19 E3 Flashcards Preview

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Flashcards in Drug Therapy With Macrolides, Ketolides, and Miscellaneous Anti-Infective Agents CH 19 E3 Deck (15)
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1

Glycylcyclines

class of anti-infective agents that are structurally related to the tetracyclines and share many of the same properties; used for the treatment of complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus and vancomycin-sensitive Enterococcus faecalis, as well as treatment of complicated intra-abdominal infections

2

Gray syndrome

dangerous condition that occurs in newborns who are given chloramphenicol; may lead to fatalities

3

Ketolides

newer class of antibiotics that belong to the macrolide group; have a more broad-spectrum effect compared to macrolides, especially Streptococcus pneumoniae infections

4

Lincosamides

similar to macrolides in their mechanism of action and antimicrobial spectrum

5

Lipopeptides

a new class of antibiotics that kills gram-positive bacteria by inhibiting synthesis of bacterial proteins, DNA, and RNA

6

Macrolides

may be bacteriostatic or bactericidal, depending on drug concentrations in infected tissues; widely used for treatment of respiratory tract and skin/soft tissue infections caused by streptococci and staphylococci

7

Methicillin-resistant Staphylococcus aureus

microorganisms resistant to broad-spectrum antibiotics such as penicillin and erythromycin; frequently colonizes nasal passages of health care workers and is increasing as a cause of infection in health care facilities

8

Methicillin-resistant Staphylococcus species non-aureus

other strains of antibiotic-resistant staphylococci

9

Methicillin-susceptible Staphylococcus aureus

methicillin-susceptible strains of Staphylococcus aureus

10

Mycobacterium avium complex

caused by atypical mycobacteria; opportunistic infection that occurs mainly in people with advanced human immunodeficiency virus infection

11

Oxazolidinones

newer class of antibiotics; active against aerobic gram-positive bacteria by inhibiting protein synthesis

12

Red man syndrome

adverse reaction when vancomycin is administered too quickly; characterized by hypotension, flushing, and skin rash

13

Streptogramins

class of antibacterial drugs; produced by Streptomyces graminofaciens bacteria

14

Vancomycin-resistant enterococci

pathogenic bacteria that are resistant to vancomycin

15

Vancomycin-resistant Enterococcus faecium

Enterococcus faecium that is resistant to vancomycin