Drug Therapy for Coagulation Disorders Ch 7 E2 Flashcards Preview

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Flashcards in Drug Therapy for Coagulation Disorders Ch 7 E2 Deck (15)
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1

Anticoagulants

drugs that prevent formation of new clots and extension of clots already present; do not dissolve formed clots

2

Antiplatelets

drugs that prevent one or more steps in the prothrombotic activity of platelets

3

Embolus

object that migrates through the circulation until it lodges in a blood vessel, causing occlusion; may be a thrombus, fat, air, amniotic fluid, a bit of tissue, or bacterial debris

4

Essential thrombocythemia

chronic blood disorder characterized by the overproduction of platelets by megakaryocytes in the absence of another cause

5

Fibrinolysin

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as plasmin

6

Hemostasis

prevention or stoppage of blood loss from an injured blood vessel and is the process that maintains the integrity of the vascular compartment

7

Heparin-induced thrombocytopenia (HIT

immune-mediated prothrombotic reaction resulting in a decrease in platelet count associated with heparin administration in patients with detectable HIT antibodies

8

Plasmin

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as fibrinolysin

9

Plasminogen

inactive protein found in many body tissues and fluids

10

Prothrombotic reaction

adverse effect that leads to thrombogenesis

11

Thrombogenesis

formation of a blood clot

12

Thrombolysis

breakdown or dissolution of blood clots

13

Thrombolytics

drugs that dissolve blood clots

14

Thrombosis

formation of a blood clot

15

Thrombus

blood clot