Drug Therapy for Coagulation Disorders Ch 7 E2 Flashcards Preview

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Flashcards in Drug Therapy for Coagulation Disorders Ch 7 E2 Deck (15)
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1
Q

Anticoagulants

A

drugs that prevent formation of new clots and extension of clots already present; do not dissolve formed clots

2
Q

Antiplatelets

A

drugs that prevent one or more steps in the prothrombotic activity of platelets

3
Q

Embolus

A

object that migrates through the circulation until it lodges in a blood vessel, causing occlusion; may be a thrombus, fat, air, amniotic fluid, a bit of tissue, or bacterial debris

4
Q

Essential thrombocythemia

A

chronic blood disorder characterized by the overproduction of platelets by megakaryocytes in the absence of another cause

5
Q

Fibrinolysin

A

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as plasmin

6
Q

Hemostasis

A

prevention or stoppage of blood loss from an injured blood vessel and is the process that maintains the integrity of the vascular compartment

7
Q

Heparin-induced thrombocytopenia (HIT

A

immune-mediated prothrombotic reaction resulting in a decrease in platelet count associated with heparin administration in patients with detectable HIT antibodies

8
Q

Plasmin

A

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as fibrinolysin

9
Q

Plasminogen

A

inactive protein found in many body tissues and fluids

10
Q

Prothrombotic reaction

A

adverse effect that leads to thrombogenesis

11
Q

Thrombogenesis

A

formation of a blood clot

12
Q

Thrombolysis

A

breakdown or dissolution of blood clots

13
Q

Thrombolytics

A

drugs that dissolve blood clots

14
Q

Thrombosis

A

formation of a blood clot

15
Q

Thrombus

A

blood clot