Néphropathie Interstietielle Chronique Flashcards

1
Q

CLinique évoquer une NTIC ?

A
  • Polyurie

- HTA apparition tardive

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2
Q

Evolution de NTIC ?

A
  • Evolution 2-4mL/min/an
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3
Q

Sd bioclinique de NIC ?

A
Leucocyturie
Absence hématurie
Altération des fonctions tubulaire
=> Polyurie / natriurèse obligatoire = perte de sel
=> Protéinurie de faible débit
=> Acidose tubulaire 

Nécrose papillaire avec hématurie macroscopique

HTA tardive

IRC

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4
Q

NIC secondaire à la prise de lithium ?

A

40% des patients sous lithium anomalie rénales après 10ans

=> Défaut de concentration avec polyurie

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5
Q

Sarcoidose ?

A
  • Hypercalcémie = Néphrangiosclérose
  • Néphrite interstitielle granulomateuse

=> CTC

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6
Q

Néphropathie herbe chinoise ?

A

RAPIDEMENT PROGRESSIF
=> Acide aristocholique

=> + favorise survenue de tumeurs urothéliales

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7
Q

Atteinte tubule proximal ?

A

Fanconi

=> Myélome
=> Plomb

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8
Q

Atteinte tubule médullaire ?

A

Défaut de concentration

=> Analgésie
=> Drépanocytose
=> Infection
=> Polykystose

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9
Q

Atteinte tubule distal ?

A

AT distale + RÉSISTANCE À ALDOSTÉRONE = AT type 4

=> Lupus / sclérodermie / Sjogren
=> Cirrhose biliaire
=> Néphrocalcinose
=> Obstruction chronique

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