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Flashcards in Treatment of Hemostasis Deck (16)
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1

COX-1 to TXA2 platelet inhibitors

Aspirin and NSAIDs

2

ADP antagonist platelet inhibitors

Ticlodipine
Clopidogrel (CYP2C19)

3

Platelet-REceptor Glycoprotein Inhibitors

Abciximab (block gp IIb)
Tirofinban (small glycoprotein inhibiting gp and fibrinogen)

4

Phosphodiesterase inhibitor

Dipyridamole (mainly used in pts w/ prosthetic valves)

5

Antithrombin III accelerator anticoagulant

Heparin (UFH)
Low Molecular Weight Heparins: (Enoxa, Dalte, Tinza-parins)
Fondaparinux (Xa inhibitor)

6

Thrombin Inhibitors

Rudins
Agatroban (treatment for HIT)

7

Vitamin K epoxide reductase inhibitor

Warfarin

8

Oral FXa Inhibitors

-Abans
Apixaban
Rivaroxaban

9

Thombolytic drusg

Streptokinase
Urokinase
Alteplase
Tenecteplase

10

Warfarin Antidote

Vitamin K,

11

Fibrinolytic inhibitor used for bleeding disorder

Aminocaproic acid

12

Protamine Sulfate is antidote for ________ because of its highly cationic charge

Heparin

13

Drugs that increase the metabolism of Wafarin S-isomer

Azoles

14

Drug type that activates warfarin because it displaces albumin and increases serum concentration of warfarin

Sulfonamides

15

Drugs that inhibit activity of Warfarin because of Drug CYP interactions

St Johns wort
Anticonvulsants

16

Reteplase is thrombolytic because it

activates plaminogen to plasmin