Lymphoid Neoplasms discreet facts Flashcards Preview

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Flashcards in Lymphoid Neoplasms discreet facts Deck (12)
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1

Most common pediatric?

precursor B cell

2

Hyperdiploidy is associated with what sort of prognosis??

good prognosis

3

t(12,21) is associated with a ________prognosis

good prognosis

4

Chronic lymphocytic leukemia cell surface markers

CD5 and CD20

5

Most common leukemia?

Chronic lymphocytic leukemia

6

Chronic Lymphocytic Leukemia presents with what histology?

smudge cells, monoclonal immunoglobulin, absolute lymphocytosis

7

Complications of Chronic Lymphocytic Leukemia

Hypogammaglobulinemia
Autoimmune hemolytic anemia
Richter Transformation: diffuse large B-cell lymphoma; (enlarged lymph node or spleen)

8

CLL even though it's a B cell leukemia expresses what T cell surface marker?

CD5+

9

t(14;18)

Follicular Lymphoma

10

BRAF mutation

Hairy cell leukemia (also in Langerhans Histiocytosis)

11

Trisomy 12

CLL/SLL prognostic marker

12

KSHV/HHV-8 associated B cell lymphoma

Assoc w/ diffuse large B cell lymphomas