Flashcards in Lymphoid Neoplasms: Follicular Lymphoma and DBCL Deck (10)
Follicular Lymphoma staining
Larger cells seen in follicular lymphomas indicate what about the lymphoma?
It has a worse prognosis
Where are the neoplastic cells in follicular lymphoma located?
Nodular infiltrate of small, cleaved lymphocytes w/ admixed large cells, incomplete mantle zone or no mantla zone at all as well as lack of tingible body macrophages allow us to distinguish follicular lymphoma from
reactive lymphoid tissue
Genetics of Follicular Lymphoma
t(14;18): overexpression of Bcl-2
Diffuse Large B cell lymphoma presents frequently w/ what sort of nodal findings
Diffuse Large B cell lymphoma is aggressive or not aggressive?
CD markers for Diffuse Large B cell lymphoma
CD 19+, CD20+, CD10+/-, CD5-, slg + (clonal)
CD markers for Follicular Lymphoma
CD19+, CD20+, CD10+, CD5-, slg + (clonal)