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Flashcards in Transcription in Eukaryotes Deck (18)
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1

Define and describe mRNA

messenger RNA, codes for proteins

2

Define and describe rRNA

ribosomal RNA, contributes to the structure of ribosomes

3

Define and describe tRNA

transfer RNA, carries AAs to ribosome

4

Define and describe snRNA

small nuclear RNA, involved in splicing

5

Define and describe snoRNA

small nucleolar RNA, involved in maturation and covalent modification of rRNAs

6

Define and describe miRNA

micro RNA, control gene expression

7

Define and describe ncRNA

other non-coding RNA, plays role in telomere synthesis, X-chromosome inactivation, transport of proteins to the ER

8

Localization and transcribed genes responsible for RNA pol 1.

- nucleolus
- rRNA 5.8S, 18S, 28S

9

Localization and transcribed genes responsible for RNA pol 2.

- nucleoplasm
- protein coding genes, miRNA, snoRNA, some snRNA

10

Localization and transcribed genes responsible for RNA pol 3.

-nucleoplasm
5S rRNA, tRNA, some snRNA, other small RNAs

11

What is the role of the 5' UTR

separates the +1 from the ATG sequence

12

What is the role of the 3' UTR

part of the last exon

13

What are the four consensus sequences in a basal promoter

BRE, TATA, INR, and DPE

14

Define BRE

B-recognition element
position: -35
binds to general tf TFIIB

15

Define TATA

position: -30
binds to general tf TBP

16

Define INR

initiator element
position: +1
binds to general tf TFIID

17

Define DPE

downstream promoter element
position: +30
binds to general tf TFIID

18

what is the primary RNA pol. used in euk?

RNA pol 2