Flashcards in DNA replication Deck (17)
What is responsible for removing erroneously placed nucleotides?
Polymerases have a P and E site. What is their respective roles?
P site: polymerization
E site: editing
What is the role of MutS and MutL?
Detects mismatched base, cuts at it and at the next nick of the sequence
Define DNA polymerase I
fills the gaps during DNA repair
DNA polymerase II role
Repairs fork stalled by DNA damage
DNA polymerase III role
How long are RNA primers
DNA helicase role
Keeps DNA polymerase on the strand synthesizing
Association between DNA helicase and DNA primase is called...
Role of DNA topoisomerase
Makes temporary breaks in DNA backbone to relieve stress of unwinding
DNA primase in eukaryotes is made of a complex of subunits named....
DNA polymerase alpha/primase
What DNA polymerase is used on the leading strand?
What DNA polymerase is used on the lagging strand?
What is the last two dimers to be added to the histone, therefore the first to come off in destabilization?
What enzyme loads H2A-H2B dimer back into the nucleosomes?