RNA structure and function Flashcards Preview

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Flashcards in RNA structure and function Deck (14)
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1

What makes ribonucleic acid different from deoxyribonucleic acid?

Ribonucleic acid has an -OH group at the second carbon on the ring

2

There is an A form and a B form of helix. Which refers to DNA and RNA respectively?

B form: DNA
A form: RNA

3

Describe the major and minor grooves on RNA respective to DNA

RNA has a much narrower and deeper major groove, and a shallower minor groove compared to DNA

4

Define group 1 of self-splicing introns

A group of self-splicing introns that release a linear form of the excised sequence

5

Define group 2 of self-splicing introns

A group of self-splicing introns that release a lariat form of the excised sequence

6

What is the characteristic structure of Type 1 self-splicing introns?

Secondary structure has 9 helices

7

What structure allows for self-cleaving of RNA?

hammerhead structure

8

If we provide excess substrate to an RNA enzyme strand, what is the observed cycle

1. Paring
2. Cleavage
3. Unpairing

9

Define 6-methyl adenosine

Located in the last exon and near to stop codon, or bound to sites for microRNAs . It is associated with the degradation of mRNAs

10

What polymerase is responsible for the production of ribosomal RNA?

RNA polymerase 1

11

Which portions of the RNA polymerase 1 are all created from the same strand?

18s (small part), 5.8s and 28s (large part)

12

What is the one part of the RNA polymerase 1 that is not part of the one strand?

5s

13

What is the role of guide RNA in the context of ribosomal RNA?

position themselves on the rRNA to attract enzymes that modify RNA

14

Guide RNA in the context of rRNA belong to what family?

small nucleolar RNAs