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Flashcards in Resilience Deck (14)
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1

Define Resilience

The ability to maintain psychobiological allostasis
The ability to adapt successfully to severe and chronic stress

2

What are some psychosocial factors associated with resilience?

Facing fears and active coping
Optimism and positive emotions
Cognitive reappraisal, positive reframing, and acceptance
Social competence and support
Purpose in life, moral compass, meaning, and spirituality

3

What are some underlying neurobiological mechansims associated with resilience?

Cognitive flexibility and control
Healthy reward signalling
Well regulated emotional responses
Optimal hormonal function
Stress inoculation
Functional fear circuitry

4

Positive life experiences promote resilience by developing:

Healthy stress axis with functional feedback
Healthy CNS structures that promote cognitive control

5

What is Stress Inoculation?

Resilience to stress through previous encounter
Short term actions of cortisol promote adaptations

6

Touch can stimulate the release of ________ ?

Endorphins (opioids)

7

Anterior Cingulate Cortex (ACC) contains receptors for _________ which when stimulated can create feeling of _________ and increase rational decision making (active coping) in that area

Opioid

Reward

8

What is Oxytocin and what effects does it have on resilience?

Love and bonding hormone
Can reduce activation in the amygdala and weaken connections with brainstem which controls some stress responses

9

The release of ________ and _________ following social interaction or touch could help regulate emotional responses, reduce stress response, increase feeling of reward and allow for rational decision making

Endorphins and Oxytocin

10

A white matter tract within the cingulate cortex that connects the frontal lobe with the temporal lobe which is stronger in resilient individuals

Cingulum

11

The Cingulum connects the _______ circuitry of the PFC and ACC with the _________ circuitry of the limbic system in the temporal lobe

Reasoning
Emotional

12

Increased activity in what cortex is consistent with a greater ability to reason, plan, enact active coping strategies, and ultimately take control as they experience stress in resilient individuals?

Prefrontal Cortex (PFC)

13

What type of genotypes are positively correlated with resilience?

Those which permit effective activation and termination of HPA axis activity

(CRH, GR genes)

14

What hormone acts at receptors in the amygdala, PFC, hippocampus, and brainstem to shut down the stress response by inhibiting the secretion of ACTH and norepineprhine?

Neuropeptide Y