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Flashcards in Schizophrenia Deck (38)
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1

A psychological disorder in which patients experience a loss of contact with reality

Psychosis

2

What is Schizophrenia ?

A classified psychotic disorder which produces disturbances in perception of reality, interpersonal relations, social integration, cognition, and mood

3

What is the prevalence of Schizophrenia?

Affects 1 in 100 people

4

Schizophrenia is highly comorbid with ________, anxiety _______, and/or ________

Depression
Anxiety
Substance Use

5

Why did Eugen Bleuler coin the term schizophrenia - which means Split Mind?

Different components of the individuals mind become disconnected from each other and reality in general

6

Behavioral excess or symptoms not experienced by non-affected individuals

Positive Symptoms

7

Behavioral deficits or impairments

Negative Symptoms

8

Erratic changes in speech, motor behavior, and emotions

Disorganized Symptoms

9

Strongly held beliefs despite overwhelming evidence to the contrary

Delusions

10

What are Bizarre Delusions?

Clearly implausible and not understandable

11

What are Non-Bizarre Delusions?

Delusions that are false but at least possible

12

What are Persecutory Delusions?

A belief that the individual is being unfairly targeted, followed, harassed, cheated, drugged, conspired against, spied on, attacked, or otherwise obstructed in the pursuit of their goals

13

Perceptions in the absence of an actual sensory stimulus

Hallucination

14

What is the most common hallucination is schizophrenia?

Auditory hallucinations

15

What are some of the Negative symptoms of schizophrenia? (The A's)

Apathy or Avolition - lack of interest/motivation

Autism - tendency to keep to oneself, no interest in people/surroundings (not the disorder)

Anhedonia - Inability to enjoy or indifference toward pleasurable activity

Affect Flattening - reduction in range/intensity of emotional expression

16

What are some of the Disorganized symptoms of schizophrenia?

Cognitive Difficulties - planning/learning/focusing

Disorganized Speech - impair effective communication

Inappropriate Affect - emotions not appropriate for current situation

Motoric Changes - unpredictable movement, agitation, and catatonic immobility

17

What are some catatonic behaviors exhibited by schizophrenics patients?

Decrease in reaction to surrounding environment

General motionless and apparent unawareness

Rigid or bizarre postures

18

DSM-5 Requirements for diagnosing schizophrenia?

Must demonstrate at least 2 of the symptoms for a minimum of 6 months (including 1 month consecutively)
Must show at least one of the first three symptoms
Must rule out - mood disorder, substance use, other medical conditions

19

What are the five DSM-5 symptoms that characterize Schizophrenia?

Delusions
Hallucinations
Disorganized Speech
Disorganized or Catatonic Behavior
Negative Symptoms

20

The first appearance of psychotic symptoms in a patient, usually when diagnosing occurs, is known as?

A Psychotic Break

21

The amount of _______ shared with an affected family member is directly related to one's risk of developing schizophrenia

DNA

22

People born in ____________ months have a 5-8% increased risk of developing schizophrenia

winter/early spring

23

There is strong correlational evidence linking prenatal infection and the development of schizophrenia in offspring, what are some of the types of infection involved?

Flu Infection
Rubella Infection
Taxoplasma Gondii Antibodies

24

Stress is a significant contributing factor to schizophrenia in regards to:

Overall risk of developing schizophrenia

As a precipitating factor in those who are susceptible

25

What are the most consistent neuroanatomical findings in schizophrenia?

Reduction in brain weight

Enlargement of the ventricles

26

What are some of the symptoms of reduced brain weight in schizophrenic patients?

Frontal and temporal lobe volume - cognitive and language deficits

Basal ganglia volume - reduced emotional control and motoric changes

Hippocampal volume - learning and memory deficits

27

There appears to be abnormal cellular organization in the schizophrenic brain, what does this suggest?

A developmental origin for the disease

The symptomatic disorganization reported may actually reflect literal cellular disorganization within the brain

28

What does the Dopamine Hypothesis of Schizophrenia propose?

That symptoms of schizophrenia are due to excess activity of dopamine

29

_________ of the mesolimbic connections (VTA -> NAc and VTA -> Hippo) results in overstimulation of the D2 receptors which results in ________ symptoms

Hyperactivity

Positive

30

________ of the mesocortical connections (VTA -> PFC) results in under-stimulation of the D1 receptors which results in ________ and ________ symptoms

Hypoactivity

Negative and Cognitive