Lecture 26 + DLA 20 Flashcards Preview

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Flashcards in Lecture 26 + DLA 20 Deck (10)
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1

What does Hardy- Weinberg assume?

1. population is large
2. random mating
3. no new mutations in the population
4. no migration of people into the population

2

What are factors that lead to genetic variation

1. new mutation
2. natural selection
3. genetic drift
4. consanguinity

3

What is an example of heterozygote advantage?

sickle cell disease

4

What is the Hardy-Weinberg equation?

p2 + 2pq + q2 = 1

5

What does p represent?

The functioning allele (homo)

6

What does q mean?

The disease causing allele (homo)

7

What group of people make up 2pq?

Carriers in the population

8

What is the founder effect?

A new mutation is presented into a small population by immigration or just a new mutation

9

What is genetic drift?

The allele may be lost or established by isolation of a population

especially if the population is small, the allele frequency may increase

10

What is genetic bottleneck?

A reduction in population that leads to a decrease in genetic diversity