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Flashcards in DLA 22 + lecture 28 Deck (42)
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1

What are the permanent residents of the connective tissue?

1. fibroblasts
2. adipose tissue
3. macrophages / monocytes
4. mast cells
5. mesenchymal stem cells

2

What are the transient cell population of the CT?

1. lymphocytes
2. plasma cells
3. eosinophils
4. basophils
5. neutrophils

3

explain fibroblasts?

they are the most common cell in connective tissue

synthesize fibers and ground substance

spindle-shaped

4

What are myofibroblasts?

wound healing

presence of contractile filaments

5

explain adipocytes?

signet ring cell

large fat inclusion

rich blood supply

6

What is an unilocular adipocyte?

One large fat droplet- white fat

7

What is an Multilocular Adipocyte?

considered brown fat

8

What is multilocular adipocytes characterized by?

1. many lipid droplets
2. central nucleus
3. rich in mito
4. highly vascular
5. rich in innervation
6. lipochrome pigments
7. heat production

9

Where is brown fat found?

body neck and abdomen of neonates

10

What are macrophages derived from?

monocytes

they migrate to CT to differentiate

11

Macrophages in CT?

liver - Kupffer cells

brain - microglia

bone - osteoclasts

12

properties of macrophages?

1. irregular cell membrane
2. have pseudopodia
3. phagocytic; produce cytokines
4. antigen presenting cells

13

Explain mast cells?

they originate in the bone marrow from precursor cells

they proliferate in the lamina propria of CT

mast cells and basophils come from the same progenitor cells

14

Explain lymphocytes?

small and spherical
condensed basophilic nucleus

immune cells - B and T

B cells develop into plasma cells

15

Explain plasma cells?

come from B lymphocytes

secretes single class of IG

basophilic cytoplasm

clock-face nucleus

negative golgi

16

eosinophils?

red granules in the cytoplasm
condensed, bilobed nucleus
phagocytosis of antibody

kills parasitic worms

17

What are the classifications of connective tissue?

1. embryonic connective tissue

2. CT proper

3. specialized CT

18

What is the embryonic connective tissue

mesenchyme- mucous connective tissue

19

What are the types of CT proper?

loose connective tissue (areolar) and dense connective tissue

20

What are the subsections of dense connective tissue?

regular and irregular

21

What are the specialized connective tissue?

1. cartilage
2. bone
3. adipose tissue
4. blood
5. hemopoietic tissue
6. lymphatic tissue

22

What are the components of connective tissue?

cells

fibers and ground substance in the ECM

23

Why is CT important?

1. support (stroma- supporting structures)

2. repair

3. Defense (immune function)

4. Nutrition (storage and transport)

24

What are the characteristics of mesenchyme?

a lot of ground substance

cells have a tapered spindle appearance

sparsely arranged reticular fibers

25

characteristics of mucous CT?

ground substance is a gelatinous consistency

few cells and fibers

mainly ground substance

26

Where is mucous CT found?

umbilical card (Wharton's jelly)

27

features of LCT?

large number of cells compared to fibers
rich blood supply

found below most epithelial linings

28

features of Dense irregular CT?

fewer cells, more fibers
no orientation of fibers

usually organ capsules, dermis, periosteum

29

features of dense regular CT?

specific orientation of fibers

imparts tensile strength

found in: tendons and ligaments

30

components of dense regular CT?

fibroblasts and type 1 collagen fibers