Flashcards in DLA 29 Deck (4)
6- mercaptopurine is used for what?
used to treat some forms of leukemia
what does the enzyme Thiopurine methyltransferase do?
this enzyme catalyzes the reaction of mercaptopurine to an inactivated form by methylation
what are some functions of mercaptopurine?
6-mercaptopurine functions by inhibition of the purine biosynthetic pathway which are needed for the formation of nucleotides, and thus production of DNA, and RNA.
In this way, 6-mercaptopurine slows proliferation