Pharmacology - Chapter 59 - Drugs for Disorders of the Adrenal Cortex

Question 1

The hormones of adrenal cortex affect multiple physiological processes. T/F?

Answer 1

True!

Question 2

Adrenal Cortex Hormones. What do they do?

Answer 2

Maintenance of glucose availability, regulate water and electrolyte balance, development of sexual characters, and life-preserving responses to stress.

Question 3

What are the Adrenal Cortex hormones?

Answer 3

Glucocorticoids (influence carb metabolism), Mineralocorticoids (modulate salt and water balance), Androgens (contribute to sexual characteristics.)

Question 4

Cushing’s and Addison’s - Def

Answer 4

Cushing’s - Adrenal hormone excess.

Addison’s - Adrenal hormone deficiency.

Question 5

Cushing’s Disease - presents with…

Answer 5

obesity, hyperglycemia, hypertension, fluid and electrolyte disturbances, etc.

Question 6

Addison’s - presents with…

Answer 6

weakness, emaciation, hypoglycemia, etc.

Question 7

Hydrocortisone - used for…

Answer 7

Adrrenal insufficiency, allergy, inflammation, chemotherapy.

Question 8

Fludrocortisone (Florinef)

Answer 8

It is a potent mineralocorticoid. It is used for Addison’s, hypoaldosteronism, congenital adrenal hyperplasia.

Question 9

What are some AE’s of Fludrocortisone (Florinef)?

Answer 9

Hypertension, Hypokalemia, Edema