Topical And I/L antiviral drugs Flashcards

1
Q

5-FU is incorporated into DNA

A

F

RNA

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2
Q

5-FU is a purine analog

A

F

Pyrimidine

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3
Q

5-FU blocks thymidylate reductase

A

F

Thymidylate synthetase

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4
Q

Bleomycin represents group of sulfur containing glycopeptide cytotoxic antibiotics

A

T

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5
Q

Bleomycin affects protein synthesis

A

T

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6
Q

Bleomycin works by binding to HPV

A

F

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7
Q

Bleomycin acts during the M and G2 phases of the cell cycle by binding to DNA

A

T

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8
Q

Podophyllin’s most active ingredient and cytodestructive agent is podophyllotoxin

A

T

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9
Q

How does podophyllotoxin work ?

A

Binds reversibly to tubulin and arrests cells in metaphase

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10
Q

Podophyllin is not contraindicated in pregnancy

A

F

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11
Q

Trichloroacetic acid works by causing hydrolysis of cellular proteins leading to inflammation and cell death

A

T

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12
Q

Cantharadin has direct viral effect

A

F

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