Orthomyxoviridae

Question 1

Influenza C

Answer 1

Contains human and swine firuses that rarely cause disease

Question 2

Influenza A

Answer 2

Contain human, equine, swine and domestic poultry viruses

Question 3

Clinical sign of what Orthomyxovirus

Answer 3

Avian Influenza

Question 4

Transmission of orthomyxoviruses in poultry

Answer 4

By ingestion and inhalation

Question 5

Isavirus

Answer 5

Contains only Infectious Salmon Anemia Virus

Question 6

Thogotovirus

Answer 6

Contain tick borne viruses which infect livestock and humans in Africa, Europe and Asia

Question 7

Equine Influenza virus replicates in

Answer 7

Epithelial cells of the upper and lower respiratory tracts

Question 8

Avian Influenza vireamia leads to

Answer 8

Multifocal lymphoid and visceral organ necrosis

Question 9

Swine influenza virus is transmitted through

Answer 9

Aerosols

Question 10

Diagonsis of Swine Influenza Virus

Answer 10

Sudden onset of clinical symptoms

Virus identification - deep nasal swab

Question 11

Diagnosis of Equine Influenza Virus

Answer 11

Clinical Presentation

RT-PCR

Question 12

Swine Influenza virus replicates in

Answer 12

Upper respiratory tract

Question 13

Genetic Shift

Answer 13

Changes in antigenic set up due to reassortment of gene segements

Question 14

Avian Influenza viruses replicate in

Answer 14

Intestinal and Respiratory Tract

Question 15

Transmission of orthomyxoviruses in mammals

Answer 15

Aerosol, droplet and fomite transmission

Question 16

Diagnosis of Avian Influenza Virus

Answer 16

RT-PCR

Question 17

Orthomyxovirus virion morphology

Answer 17

Pleomorphic

Segmented genome

Two types of glycoprotein spikes

Question 18

T/F: Influenza virues are sensitive to heat, acidic pH and lipid solvents

Answer 18

True

Question 19

Influenza B

Answer 19

Contain human viruses

Question 20

Clinical signs of low pathogenic avian influenza

Answer 20

Cause upredictable losses do to decreased egg production

Question 21

Transmission of orthomyxoviruses in aquatic birds

Answer 21

Virus is shed in feces - fecal oral transmission

Question 22

Genetic Drift

Answer 22

Changes in antigenic setup due to point mutations - nucleotide substitution, deletion, insertions

Question 23

Clinical signs of High pathogenic avian influenza

Answer 23

Cause sudden death without symptoms

Cessation of egg production, lacrimation, diarrhea, edema, cyanosis, torticollis

Question 24

Why are pigs considered “mixing vessels” for influenza viruses

Answer 24

Because of their ability to become co-infected with both avain and human strains of influneza virus

Question 25

Transmission of Thogotoviruses is by

Answer 25

Ticks - replication in both tick and mammal

Question 26

Classification of Orthomyxoviruses is based on

Answer 26

The type of hemagglutinin and Neuraminidase

________________________

16 possible hemagglutinin

9 possible neuraminidase

Question 27

Symptoms of Swine Influenza Virus

Answer 27

Appears in many animals at the same time

Fever

Nasal Discharge

May develop pneumonia and die

Question 28

Most important viral respiratory disease of horses

Answer 28

Equine Influenza Virus

Question 29

Avain Influenza Viruses are characterized as

Answer 29

Highly Pathogenic

Low Pathogenic

Question 30

Clinical signs of Equine Influenza Virus

Answer 30

Rapidly spreads

Fever

Reddening of nasal mucosa

Conjunctivitis

Serous nasal discharge

Dry paroxysmal cough

Abortion

Question 31

Transmission of Isavirus

Answer 31

Transmitted in water