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FMP1 A&P > Conception & Fetal Development > Flashcards

Conception & Fetal Development Flashcards

1
Q

After ovulation, the ruptured follicle collapses and forms what?

A

The corpus luteum

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2
Q

What does the corpus luteum do?

A

Secretes progesterone and oestrogen

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3
Q

What happens to the corpus luteum if pregnancy does not occur?

A

Degenerates in 10 days, leaving a scar called corpus albicans

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4
Q

What happens to the corpus luteum if pregnancy does occur?

A

It produces hormones until the placenta takes over the role at about week 10 of pregnancy

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5
Q

Explain the process pre-conception

A
  • ovulation, an oocyte is in the fallopian tube
  • spern ejaculated into vagina and some cross the cervical os and entered fallopian tubes
  • before fertilisation sperm undergoes two maturational changes
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6
Q

What are the two maturational changes sperm undergoes before fertilisation?

A

Capacitation and acrosome reaction

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7
Q

Explain sperm maturation - Capacitation

A
  • degeneration of the membrane over the acrosome (sperm head)
  • stimulated by chemical within female genital tract
  • increases mobility of sperms tail
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8
Q

Explain sperm maturation - acrosome reaction

A
  • binding a sperm to the zona pellicuda triggers the acrosome reaction
  • release of enzymes prior to the binding disperse to corona radiate
  • following binding enzymes, sperm digests and penetrates a path to egg cell
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9
Q

What is the zona pellicuda?

A

outer layer of the ovum, jelly-like layer

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10
Q

What is the corona radiate?

A

The outermost layer of the ovum

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11
Q

What occurs upon entry of sperm during fertilisation?

A

the ovum nucleus swells, creating the female pronucleus. The sperm nucleus is released in the cytoplasm of the oocyte and the two nuclei approach each other

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12
Q

What makes the female and male nuclei both ‘haploid’?

A

They contain 23 chromosomes

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13
Q

What are the fused nuclei named as the conceptus (product of fertilisation)?

A

Zygote

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14
Q

The zygote is ‘diploid’ because..

A

It holds 46 chromosomes

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15
Q

Within 24 hours what happens to the zygote?

A

undergoes mitosis and splits into 2 smaller cells

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16
Q

What is the process of the zygote splitting called?

A

cleavage

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17
Q

What is the name of the smaller cells of zygote called when split?

A

blastomeres

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18
Q

The zygote continues cleaving, dividing into:

A
  • 2 cells within 24 hours
  • 4 cells within 48 hours
  • 8 cells within 60 hours
  • 16 cells within 72 hours
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19
Q

What is the zygote known as at the point of 16 cell division?

A

Morula

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20
Q

The zygote structure has not increased in size despite cleavage. How?

A

The cells become more compact

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21
Q

During the development of the blastocyst (morula) what is the process of cavitation?

A

occurs where the outer cells secrete fluid into the moral creating a fluid filled cavity

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22
Q

What is the name of the fluid filled cavity made through cavitation?

A

blastocyst

23
Q

When does the formation of the blastocyst occur?

A

When there is at least 32 cells - cleavage

24
Q

What is the blastocyst composed of?

A
  • a single layer of trophoblasts (flattened outer cells)

- an inner cell mass, embryoblast

25
Q

What do the trophoblasts form?

A

the placenta and chorion

26
Q

What do the embryo blasts form?

A

the embryonic disc including umbilical cord and amnion

27
Q

Define chorion?

A

Outermost layer of membranes surrounding the embryo

28
Q

Define amnion?

A

The amnion is membrane that covers the embryo when first formed. Fills with amniotic fluid which causes the amnion to expand and become the amniotic sac

29
Q

When does implantation occur?

A

Between day 6 and 14 after ovulation

30
Q

What allows implantation to occur?

A

when the trophoblasts adhere to/stick to the prepared endometrium

31
Q

Implantation can result in…

A

a small amount of vaginal bleeding that can be mistaken as menstruation - known as implantation bleed

32
Q

Day 14 when implantation is complete, what begins to develop?

A

The placenta (trophoblast cells)

33
Q

Define ‘embryo’

A

this term refers to the conceptus form implantation until 8 weeks after conception

34
Q

By week 2 the embryo blast cells differentiate into 2 types of cells:

A

epiblasts and hypoblasts

35
Q

What do the epiblast and hypoblast cells form?

A

Bilaminar embryonic disc

36
Q

What does the hypoblast cells form?

A

The umbilical vesicle (sac) and umbilical cord

37
Q

What does the epiblast cells form?

A

the amnion

38
Q

What does the umbilical vesicle do that is formed by hypoblast cells?

A
  • provides nourishment
  • forms part of digestive system
  • produces earliest blood cells and vessels
39
Q

What does the amnion do formed by the epiblast cells?

A

grows more rapidly than the embryo and surrounds it

40
Q

Define ‘organogenesis’

A

Development of the embryo

41
Q

What happens to the bilaminar embryonic disc around day 15

A

further differentiation enables the inner cell mass to become the trilaminar embryonic disc

42
Q

What are the 3 primary germ layers of the trilaminar embryonic disc?

A
  • ectoderm
  • mesoderm
  • endoderm
43
Q

What does the ectoderm layer do within the trilaminar embryonic disc?

A

forms structures of nervous system, skin epidermis, hair and nails

44
Q

What does the mesoderm layer do within the trilaminar embryonic disc?

A

forms the skeleton, muscles, connective tissues, kidneys, heart, lymph, dermis of skin, blood and blood vessels

45
Q

What does the endoderm layer do within the trilaminar embryonic disc?

A

forms the epithelial layer of digestive, respiratory and urogenital systems and glandular cells of liver and pancreas

46
Q

Define ‘embryonic folding’

A

the disc results in a tube from a change of shape and relationship of the organs - after 4 weeks

47
Q

Fetal Development: Weeks 8-12

A 
Eyelids develop
Kidneys begin to function
Passing urine from week 10
Fetal circulation functioning
Sucking and swallowing begins
Lanugo appears (thin hair)
Moves freely
Gaining weight
Fetal heart rate heard
48
Q

Fetal Development: Weeks 12-16

A

Skeletal development
Meconium present in gut (first stool)
Nasal septum and palate fuse
Sex distinguishable

49
Q

Fetal Development: Weeks 16-20

A 
‘Quickening’ - mother feels movement 
Fetal heart easily heard on auscultation
Vernix appears
Fingernails can be seen
Skin cells begin to be renewed
50
Q

Fetal Development: Weeks 20-24

A

Periods of sleep and activity
Respond to sound
Skin red and wrinkled

51
Q

Fetal Development: Weeks 24-28

A

Survival can be expected if born
Eyelids open
Respiratory movements

52
Q

Fetal Development: Weeks 28-32

A

Begins to store fat and iron
Testes descend into the scrotum
Lanugo disappears from face

53
Q

Fetal Development: Weeks 32-36

A

Increased fat make the baby more rounded
Lanugo disappears from the body
Nails reach tips of fingers
Head hard lengthens
Producing surfactant to help lung inflate at birth
Weight gain 25g per day
Plantar creases visible - i.e. creases in hands and feat

54
Q

Fetal Development: 36-40 weeks

A

Contours rounded
Skull fully formed by soft and pliable - so the plates can override making the head as small as possible for birth
At ‘term’ - birth is due

FMP1 A&P (31 decks)

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