Exam 2; Aggressive Periodontitis

Question 1

What are the overall characteristics of AP

Answer 1

non-contributary medical history
rapid attachment and bone loss
familial aggregation
lack of consistency between bacterial deposits and severity of breakdown

Question 2

This is important when recognizing AP

Answer 2

early detection

Question 3

Which group of people is more prone to AP

Answer 3

children/adolescents

Question 4

What are four specific indicators of AP

Answer 4

marginal bone loss
presence of clinical attachment loss
increased probing depths
plaque

Question 5

There is an absence of this when diagnosing the localized form of AP

Answer 5

systemic disease that may severely compromise host response or lead to premature exfoliation of teeth

Question 6

What is the distribution of localized AP

Answer 6

not more than 2 teeth are affected in addition to the first molars and incisors

Question 7

What is the clinical outcome of LAP

Answer 7

severe destruction of periodontal tissues in a short time

Question 8

What are two possible reasons for destructive process

Answer 8

aggressive causative agents

high level of susceptibility

Question 9

What is one of the main bacterial etiologies in LAP

Answer 9

AA

Question 10

This is one of the main pathologies of AA

Answer 10

leukotoxin

Question 11

These levels are pretty high in regards to AA

Answer 11

Ab levels

IgG2 levels

Question 12

What are some genetic factors of LAP

Answer 12

familial aggregation
most likely substantial genetic polymorphism
proposed model = autosomal dominant

Question 13

This has been shown to increase the likelihood of GAP but not so much LAP

Answer 13

smoking

Question 14

L/GAP is what type of factorial disease

Answer 14

multifactorial disease

Question 15

L/GAP can result from an imbalance in what

Answer 15

host genes and environment

Question 16

This is necessary to cause L/GAP

Answer 16

exposure to a pathogen and the host’s inability to deal with it to avoid damage

Question 17

This of L/GAP is determined by modifying environmental (smoking) or genetic factors

Answer 17

phenotype

Question 18

What is the pathogenesis of AP

Answer 18

normal to LAP to GAP

Question 19

What two things can cause normal to go to LAP

Answer 19

exposure to bacterial infection; AA

genetic predisposition

Question 20

What three things can cause LAP to go to GAP

Answer 20

smoking
other bacteria
genetic modifying factors

Question 21

What are some questions to answer when diagnosing L/GAP

Answer 21

is there periodontitis
match of plaque/calculus/local factors with periodontal destruction
systemic component
microbiological diagnosis
other family members
host defenses

Question 22

What are four treatment principles of L/GAP

Answer 22

referral to a periodontist
elimination or suppression of microflora
address environmental factors
provide environment conducive to long term maintenance