menopause and premature ovarian insufficency

Question 1

at birth all primoidal oocytes are

Answer 1

primoidal

Question 2

primoidal oocytes arrested when

Answer 2

prophase 1 meiosis

Question 3

how is secondary oocyte formed

Answer 3

meiosis 1

Question 4

meiosis 2 completes when

Answer 4

egg is fertilized

Question 5

how is trioploidy extruded

Answer 5

second polar body extruded after meiosis 2

Question 6

stages of ovarian cycle

Answer 6

follicullar
ovulatory
luteal

Question 7

stage of uterine cycle

Answer 7

menstration
proliferative
secretary phase

Question 8

men gamete difference

Answer 8

no gamete exhaustion

no sudden fall in fertility

Question 9

menopause is

Answer 9

last menstrual period

Question 10

menopause measured how

Answer 10

no periods for a year

Question 11

how to diagnose menopause

Answer 11

perimenopause vasomotor symptoms and irregular bleeding

diagnosis harder in women taking hormone meds

Question 12

menopause what happens

Answer 12

due to limited oocytes
less oocyte less estrogen
fsh increase

Question 13

menopause leads to

Answer 13

anoulutory cycles
physical changes
psycological changes

Question 14

menopause technical term

Answer 14

hypoestrogenism

Question 15

hypoestrogenism symptoms

Answer 15

hot flush
headaches
palpitations
cramps
urogenital symptoms
mood change 
libido down

Question 16

average age

Answer 16

52

Question 17

women spend what% of their life in menopause

Answer 17

1/3

Question 18

longterm consequence

Answer 18

osteoporosis
cardiovascular disease
vaginal dryness\atrophy
alzheirs

Question 19

treatment options

Answer 19

oestrogen
prodesterone
testosterone

Question 20

benefit of hormonal treatment

Answer 20

protect bones
aleiviate symptomsreduces risk colorectal cancer
protect cvd

Question 21

risk of hormonal treatment

Answer 21

breast cancer

endometrial cancer

Question 22

2 types hormonal treatment

Answer 22

oral (implant/local)

transdermal

Question 23

premature ovarian insufficiency is

Answer 23

premature menopause

premature ovarian failure

Question 24

diagnosis for premature ovarian insufficiency

Answer 24

amenorrhoea 4 months

FSH >30 U/L on 2 occasions

Question 25

incidence i under 40s

Answer 25

1%

Question 26

incidence i under 30s

Answer 26

0.1%

Question 27

incidence i under 20

Answer 27

0.01”%

Question 28

is POI and early menopause the same thing

Answer 28

NO

Question 29

treatment POI

Answer 29

hormone replacement
fertility treatmetn
psycological

Question 30

what % POI cause identified

Answer 30

70%

Question 31

what% POI is familal

Answer 31

30

Question 32

What repeat is responisble

Answer 32

55-200 cggg repeat

Question 33

heritable?

Answer 33

highly

Question 34

environmental

Answer 34

1-2 year effect max

Question 35

where genes

Answer 35

mitochondria codes for 37 genes including POI