Heme/Onc Flashcards
1
Q
Cancer is the ______cause of childhood mortality
A
2nd
2
Q
Which type of cancer is the most likely to cause cancer death in children?
A
brain/CNS
3
Q
in the US, what is the most common cancer in children?
A
acute leukemia
ALL - 75% (boys a bit higher than girls)
AML - 20%
4
Q
what is the pathophysiology of acute leukemia?
A
blast proliferation in marrow interferes with RBC production and abnormal WBC and uric acid accumulation as blast cells break down
5
Q
why don’t we use radiation therapy in pediatrics much anymore?
A
stunts CNS growth - microcephaly
only done if CNS involvement is present at the start (rare)
6
Q
A
