Wk 11 Antiseizure Flashcards Preview

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Flashcards in Wk 11 Antiseizure Deck (40)
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31

31. Name the contraindications for phenytoin (Dilantin)?

Bradycardias and heart blocks.

32

32. What pregnancy category is phenytoin (Dilantin)?

Category D

33

33. What would you tell a woman who is taking phenytoin (Dilantin) and oral contraceptives?

Phenytoin (Dilantin) reduces the blood levels of oral contraceptives. Use backup contraception.

34

34. What seizures are affected by carbamazepine?

Tonic-clonic, partial, and complex partial seizures.

35

35. What is the mechanism of action for carbamazepine (Tegretol)?

Delays recovery of sodium channels.

36

36. How does carbamazepine (Tegretol) influence hepatic metabolism?

Carbamazepine (Tegretol) induces (speeds up) hepatic metabolism of other drugs.

37

37. What pregnancy category is carbamazepine (Tegretol)?

Category D

38

38, What antiepileptic drug should not be used during pregnancy? Why? What preventative measure is recommended?

Valproic acid. Causes neural defects and lowers IQs. Take folic acid 5 mg daily in case becomes pregnant.

39

39. What organ dysfunctions may be precipitated by valproic acid?

Hepatotoxicity and pancreatitis.

Hepatotoxicity and pancreatitis.

40

40. What is the first drug recommended for acute seizure management? Why?

Lorazepam (Ativan). Lasts 72 hours.