Renal Physiology Flashcards Preview

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Flashcards in Renal Physiology Deck (110)
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1

________ is an enzyme produced by JG cells.

Renin is an enzyme produced by JG cells.

1

Inulin

Used to calculate GFR

Gold Standard by renal physiologists

Not used in veterinary medicine

Involves urine collection

2

There should never be _________ in the urine.

There should never be glucose in the urine.

2

The ____________ receives virtually all blood because it is where filtration and modification occur.

The cortex receives virtually all blood because it is where filtration and modification occur.

2

Water is unimpeded by the filtration apparatus thus is said to be __________.

Water is unimpeded by the filtration apparatus thus is said to be freely filterable.

2

Steroid effect on prostaglandins

Blocks PLA2 enzyme activity

3

Increased Creatinine primarily caused by

Decreased H2O in the blood 

Decreased filtration by the kidney

4

Parasympathetic nervous system _______ heart rate.

Parasympathetic nervous system decreases heart rate.

5

Why do we calculate GFR?

1. Acute Renal Disease

2. Chart progression of Chronic Renal Disease

5

Water is not reabsorbed at the ___________.

Water is not reabsorbed at the ascending loop of henle.

6

______________: events in the renal tubules influence the RBF and GFR.

Tubuloglomerular Feedback: events in the renal tubules influence the RBF and GFR.

6

Relationship between plasma [creatinine] and GFR

Increased plasma [creatinine] = decreased GFR

6

SDMA

Used for earlier diagnosis of CKD

Put into blood stream all of the time by all cells during protein degredation

Excreted exclusively by kidney

7

___________: cells of the mascula densa maintain RBF by monitoring [Na+, K+ and Cl-]

Humoral Response: cells of the mascula densa maintain RBF by monitoring [Na+, K+ and Cl-]

8

Increased CHP due to systemic pressure = __________ GFR.

Increased CHP due to systemic pressure = increased GFR.

8

__________ causes increased PGC, increased GFR and decreased RBF.

Constriction of Efferent Arteriole causes increased PGC, increased GFR and decreased RBF.

9

Great increase in CHP due to efferent arteriole tone = ____________ GFR.

Great increase in CHP due to efferent arteriole tone = decreased GFR.

_________________

Increase in resistance decreases flow (occlusion)

10

Increased CHP due to afferent arteriole tone = ___________ GFR.

Increased CHP due to afferent arteriole tone = increased GFR.

10

Increased [Na+, K+, Cl-] tells the mascula densa that there is _________ GFR.

Increased [Na+, K+, Cl-] tells the mascula densa that there is increased GFR.

11

Podocytes are found within the viseral epithelium of ___________.

Podocytes are found within the viseral epithelium of Bowman's Capsule.

11

What are the two types of nephrons in the kidney?

Cortical and Juxtamedullary

12

_________ is the most important parameter in determination of normal renal function

GFR is the most important parameter in determination of normal renal function

13

Juxtaglomerular (JG) cells are found in the _____________ of the kidney.

Juxtaglomerular (JG) cells are found in the afferent arteriole of the kidney.

14

NSAIDs effect on prostaglandins

Indescriminant COX blocker

Decrease blood flow to the kidney

Cause GI ulcer

Decrease blood clotting

15

Layers of the "filter"

1. Fenestrations

2. Basement Membrane

3. Filtration slits

16

Under normal conditions ________ is essentially zero.

Under normal conditions BSCOP is essentially zero.

18

Amount of plasma in should __________ the amount of plasma out of the kidney (in a normally hydrated animal.)

Amount of plasma in should equal the amount of plasma out of the kidney (in a normally hydrated animal.)

19

Describe the stretch reflex

Stimulus > Afferent Neuron > Brain > Preganglionic Neuron > Postganglionic Neuron > Effector Organ

20

Urine is produced when

All the time

21

___________ responds to decreased [Ca++] to maintain overall Ca++ homeostasis.

Parathyroid Hormone (PTH) responds to decreased [Ca++] to maintain overall Ca++ homeostasis.