Renal Physiology 2 Flashcards Preview

RUSVM Physiology II > Renal Physiology 2 > Flashcards

Flashcards in Renal Physiology 2 Deck (151)
Loading flashcards...
1

___________: only a fraction of the plasma presented to the glomeruli is filtered.

Filtration Fraction: only a fraction of the plasma presented to the glomeruli is filtered.

2

________ of plasma is filtered.

20-30% of plasma is filtered.

3

Filtration rate is measured in units of _______.

Filtration rate is measured in units of mL/min.

4

Secretion, Reabsorption and Excretion are measured in units of _________.

Secretion, Reabsorption and Excretion are measured in units of mg/min.

5

Excretion (E) =  _______________

Excretion (E) =  Filtration (F) + Secretion (S) - Reabsorption (R)

6

___________: maximum rate at which nephron epithelium can remove substances from plasma and secrete them into filtrate

Transport Maximum: maximum rate at which nephron epithelium can remove substances from plasma and secrete them into filtrate

7

Secretion transport is dependent on

Secretion transport is dependent on the number/density of membrane transporters that allow for secretion or reabsorption

8

When transport maximum is reached, substances that should be secreted _____________.

When transport maximum is reached, substances that should be secreted accumulate in plasma.

9

When transport maximum is reached, substances that should be reabsorbed __________.

When transport maximum is reached, substances that should be reabsorbed may be lost in urine.

10

"Splay" in graphs of [Glucose] reflects what

Heterogenicity of nephrons

11

Glucose in the urine can be due to:

Hemorrhage

Increased [Glucose} in plasma

Proximal tubule damage

12

Explain how Fight or Flight response increases plasma glucose

SNS stimulation releases epinephrine that increases glycogenolysis at the liver.

13

Why is the Fight or Flight response important in some species and not others in regards to [Glucose]

In some species the [Glucose] in plasma caused by the Fight or Flight response exceeds transport maximum

14

In what species is the Fight or Flight Response important to be aware of in regards to [Glucose]

Bovine

15

_______ is secreted when there is increased [Glucose] in plasma.

Insulin is secreted when there is increased [Glucose] in plasma.

16

[Glucose] in plasma and Filtration of Glucose is a __________ relationship.

[Glucose] in plasma and Filtration of Glucose is a linear relationship.

17

Normal [Glucose] in plasma for dog

70-100 mg/dL

18

Glucose Transport Maximum of dog

180-200 mg/dL

19

Decreased transport maximum means what in regards to the concentration of a substance in plasma.

More of the substance is excreted in urine when it is increased in plasma.

20

The _________ is the major portion of the nephron responsible for reabsorption and secretion.

The proximal tubule is the major portion of the nephron responsible for reabsorption and secretion.

21

The _______ does not modify osmolarity.

The Proximal Tubule does not modify osmolarity.

22

__________ of water is reabsorbed at the proximal tubule.

50-80% of water is reabsorbed at the proximal tubule.

23

_________ work at the proximal tubule to increase reabsorption of water.

NE, E, AGII work at the proximal tubule to increase reabsorption of water.

24

Increased reabsorption at the proximal tubule can be due to

Decreased blood pressure

Increased osmolarity

25

_______ of water is reabsorbed at the dLoH

20% of water is reabsorbed at the dLoH

26

At the ______ there is more water reabsorption than osmolyte.

At the dLoH there is more water reabsorption than osmolyte.

27

The ________ is considered a passive structure.

The dLoH is considered a passive structure.

28

Filtrate at the dLoH is _____osmotic.

Filtrate at the dLoH is hyperosmotic.

29

Urea from the MCD is secreted at the ________.

Urea from the MCD is secreted at the dLoH.

30

The _______ puts solute into the interstitium.

The aLoH puts solute into the interstitium.