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Flashcards in Psych Shelf Deck (102)
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1

What is the difference between acute stress disorder and PTSD?

Acute stress disorder, sx 1mos

2

What are the 4 symptoms of PTSD?

1. Anhedonia
2. Hypervigilence
3. Avoidance
4. Flashbacks

3

How to you control symptoms in PTSD?

Psychotherapy!!! numero uno!
- also SSRIs
and if panic attacks: BZDs

4

In what instances is clozapine (and other atypicals) more effective than the typical antipsychotics?

For the treatment of refractory psychotic disorders

5

What symptoms are the atypical antipsychotics better at treating?

The negative symptoms

6

Other than tx psychotic disorders, what else can antipsychotics be used for?

1. Bipolar disorder
2. Delirium
3. Tourette's
4. PTSD
5. Transient psychotic symptoms in personality disorders

7

Antipsychotic potency correlates with what?

Potency of dopaminergic receptor blockade

8

How is risperidone similar to typical antipsychotics?

very potent blocker of D2 receptor with relatively less serotonin activity

9

What are the first line agents for acute psychosis?

oral preparations of the atypical antipsychotics

10

which medication is used in patients who have failed other antipsychotics?

clozapine

11

What medications are used for acute agitation in schizophrenia?

1. Aripiprazole
2. Olanzapine
3. Ziprasidone
(IM)

12

Which drugs are approved for the treatment of the manic phase of bipolar disorder?

1. Aripiprazole
2. Chlorpromazine
3. Olanzapine
4. Quetiapine
5. Risperidone
6. Ziprasidone

13

Which drugs are approved for the treatment of the depressive phase of bipolar disorder?

1. Combination of olanzapine-fluoxetine
2. Quetiapine

14

Generally speaking, what are the differences in SE profiles of the typical versus atypical antipsychotics?

typicals = movement disorders
atypicals = sedation and metabolic effects

15

which antipsychotic has the greatest anticholinergic side effects?

- low potency, typical antipsychotics (chlorpromazine)

16

which antipsychotics lower the seizure threshold?

low potency, typical antipsychotics and clozapine

17

What antipsychotic causes hypotension and how does it do so?

Risperidone: via alpha receptor blockade

18

Which antipsychotic is associated with agranulocytosis?

Clozapine! most efficacious but last line drug bc of side effects

19

Which antipsychotics can cause QT prolongation?

1. Ziprasidone
2. Low potentcy typical antipsychotics: thioridazine and mesoridazine
3. Risperidone

20

what antipsychotic causes myocarditis and when does it occur?

Clozapine- early in treatment

21

which antipsychotics are associated with metabolic effects (weight gain, dyslipidemia, and adult onset diabetes)

Olanzapine and closapine

22

Which antipsychotic can cause pigmentary retinopathy?

Thioridazine

23

Which antipsychotic can increase the risk of developing cataracts?

Quetiapine

24

What are the atypical antipsychotics? (7)

"Oh, Crap! QZ"
Olanzapine
Clozapine
Risperidone
Aripiprazole
Paliperidone
Quetiapine
Ziprasidone

25

What is the difference w hallucinations between schizophrenia and psychosis 2ndary to a general medical condition?

Schizophrenia = mostly auditory hallucinations
2ndary to GMC = prominent hallucinations and delusions, sx only occur during episodes of delirium

26

Difference between delusion, illusion, and hallucination

Delusion: fixed false belief
Illusion: misinterpretation of an external stimulus
Hallucination: perception in the absence of an external stimulus

27

What endocrinopathies can cause psychosis?

1. Addison/Cushing disease
2. Hyper/hypothyroidism
3. Hyper/hypocalcemia
4. Hypopituitarism

28

Medications that could cause psychosis?? (9 classes)

1 Corticosteroids
2. Antiparkinsonian agents
3. Anticonvulsants
4. Antihistamines
5. Anticholinergics
6. Some antihypertensives: beta blockers
7. Digitalis
8. Methylphenidate
9. Fluoroquinolones

29

What are the 3 phases of schizophrenia?

1. Prodromal: decline in functioning that precedes first psychotic episode
2. Psychotic
3. Residual: occurs between episodes of psychosis, flat affect, social withdrawal, odd thinking, can continue to have hallucinations

30

Only one other sx (rather than 2) is required in what 3 conditions?

1. If delusions are bizarre
2. Hallucinations consist of a voice keeping up a running commentary of a persons behavior
3. Two or more voices conversing with one another