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Flashcards in exam 7 Deck (13)
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1

glyburide

sulfonylurea that inhibits Katp channel

2

rapaglinide

meglitinide that inhibits katp channel

3

"glitazone"

PPARy agonist --> inc insulin sensitivity

4

acarbose

a-glucosidase inhibitor --> inhib breakdown of carbs + oligosaccharides

5

pramlitide

amylin --> sup glucagon, dec gastric emptying

6

exendatide

GLP-1 agonist --> inc insulin syn, dec gastric emptying

7

sitagliptin

DPP-4 inhibitor --> inc incretin --> inc insulin + dec glucagon

8

canagliflozin

SGLT2 inhibitor --> dec glucose reab

9

hydralazine

dec afterload, post MI

10

nitroprusside

dec preload + afterload, ICU via IV

11

nesiritide

vasodilate (inc cGMP) + diuretic, ICU via IV

12

isosorbide dinitrate + nitroglycerin

dec preload, long term=tolerance

13

vaptans (ADH antag)

IV tx of hospitalized pt with hyponatremia + CHF + syndrome of inappropriate ADH secretion, DONT REDUCE MORTALITY