Chapter 6 BNF (Sex Hormone Responsive Conditions)

Question 1

Name some natural Oestrogens?

Answer 1

Estradiol
Estriol
Estrone

Question 2

Name some synthetic Oestrogens?

Answer 2

Ethinylestradiol

Menstranol

Question 3

What’s the treatment for vaginal atrophy?

Answer 3

Topical Oestrogens

Question 4

What are the vasomotor symptoms Postmenopause ?

Answer 4

Hotflushes

Night sweats

Question 5

What’s the treatment of vasomotor symptoms?

Answer 5

Systemic oestrogens

Patches

Clonidine

Question 6

Where must oestrogen patches be applied?

Answer 6

Below waistline

Away from breast

Question 7

Which HRT is recommendations for patients with no uterus?

Answer 7

Oestrogen only!

Question 8

What type of combined HrT are available?

Answer 8

Cyclical or continuous

Question 9

Which type of continuous HRT is recommended in peri menopausal women and women less than 12 months after last period ?

Answer 9

Cyclical

Question 10

When should HRT be stopped before surgery?

Answer 10

4-6 weeks

Question 11

Does HRT provide contraception?

Answer 11

No

Question 12

What contraception is recommended in under 50 and over 50?

Answer 12

Under: combined (low oestrogen)

Over: barrier

Question 13

What are side effects of HRT?

Answer 13

Ovarian
Breast
Cervical
Endometrial (add progestogen)

CHD: if started 10 years post menopause

Question 14

What are some reasons to stop HrT?

Answer 14

VTE 
Stroke
Liver 
BP (160/95) 
Cancer

Question 15

What’s clomifene used for?

Answer 15

Ovulation stimulant

6 cycles