Hematology cell types Flashcards

1
Q

Burr Cells (Enchinocytes)

A

Uremia, Hypomag., hypophos, HUS

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2
Q

Hypersegmented Neutrophils

A

Megoblastic Anemia (Folic Acid/B12)

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3
Q

Schistocytes

A

TTP, DIC

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4
Q

Auer Rods

A

AML

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5
Q

Codocytes (Target Cells)

A

B-Thalassemia

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6
Q

JAK-2

A

Polycythema Vera (increase in x3 myeloid lines)

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7
Q

Downey Cells

A

Infectious Mono., EBV, cytomegalovirus

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8
Q

Koilonychia

A

Fe+ def. anemia (spoon shaped nails)

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9
Q

Philadelphia Chromosome

A

CML

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10
Q

Howell-Jolly Bodies

A

Damaged spleen - Hereditary spherocytosis (Dx w/ with osmotic fragility test)

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11
Q

Heinz Bodies

A

G6PD def., uremia

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12
Q

Rouleaux formation

A

Multiple Myeloma, Waldenstrom’s

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13
Q

Smudge Cells

A

CLL

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14
Q

Reed-Sternberg (Owl eyes)

A

Hodgkin’s Lymphoma and Minimal Change DZ

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15
Q

Basophilic Stippling

A

B-Thalassemia, lead poisoning, megaloblastic anemia

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16
Q

Bence-Jones proteins

A

Multiple Myeloma

17
Q

low hematocrit with reticulocytosis

A

Damaged spleen - Howell-Jolly bodies

18
Q

Direct Coombs test

A

Detects antibodies for RBC’s in autoimmune hemolytic anemia

19
Q

Indirect Coombs test

A

Detect antibodies for RBC’s in pregnant women (Rh)

20
Q

Treated with phototherapy in neonatal period

A

Hereditary spherocytosis

21
Q

Restrict activity that might cause trauma

A

ITP, EBV, damage to spleen

22
Q

Chocolate colored blood

A

Methmoglobinemia Tx with Methylene blue

23
Q

hydroxyurea

A

Tx for Sickle pain prevention. Increases HbF

24
Q

Decreased haptoglobin

A

G6PD def. and hereditary spherocytosis

25
Q

prolonged bleeding time, low platelet count, and increased PT and PTT.

A

DIC and Protein C

26
Q

Recurrent DVTs

A

Factor V Leiden

27
Q

left-shifted myeloid series in middle-aged patients, causing fatigue, night sweats, and low-grade fevers

A

CML

28
Q

BLASTS

A

Think of a leukemia