ch 16 frontal lobe Flashcards

1
Q

anatomy

A

tissue anterior to central sulcus-motor, premotor, prefrontal

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2
Q

subdivisions

A

premotor and supplementary motor cortex, frontal and supplementary eye field

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3
Q

prefrontal cortex

A

area of the frontal lobe that receives input from the dorsomedial nucleus of thalamus
divisions: dorsolateral inferior, medial

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4
Q

motor area connections

A

projects to spinal motor neurons, cranial nerves that control the face, basal ganglia and red neuclues

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5
Q

premotor area connections

A

direct movement through coticospinal projections or motor projections, gets input from posterior parietal regions and dorsolateral prefrontal area

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6
Q

eye fields

A

receive from PG and superior colliculus

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7
Q

all premotor areas get projections from

A

dorsolateral prefrontal cortex–controls eye and limb movement

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8
Q

prefrontal area connections

A

end points of ventral (object recognition) and dorsal (spatial info) visual streams
dorsolateral prefrontal area-reciprocal connections with post pari and STS, extensive connections with cingulate cortex, basal ganglia, superior colliculus, input from dopamingeric cells in tegmentum

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9
Q

orbital frontal cortex connections

A

input from temporal lobe, amygdala, gustatory cortex, somatosensory cortex, olfactory cortex, dopamingeric cells in tegmentum, projects to hypothalamus and amygdala

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10
Q

theory of function for frontal lobe

A

planning and selecting, persistence and ignoring other stimuli, keeping track of whats been done–all executive functions, responds to internal external and context clues

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11
Q

theory of function for preomotor cortex

A
  • selects movements to be executed, choose behavior in response to external cues, increase in premotor activity when cues are associated with movement
  • supplementary motor role in selecting and directing internal motor sequences
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12
Q

prefrontal cortex functions

A
  • controls cognitive processes so that appropriate movements are selected at correct time
  • internal cues-temporal memory (what has just happened, can be related to things or movements), prefrontal cortex, dorsolateral
  • external cues-feedback about rewarding properties of stimuli, orbital frontal cortex learning by association, with memory damage use external cues to know how to act
  • context clues-orbital frontal, social interactions, detailed sensory info to inferior from temp lobe/affective cortex(amyg)
  • autonoetic awareness-self knowledge, continuous
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13
Q

motor___movements
premotor___movements
prefrontal____movements___

A

makes
picks
makes sure, done at right time and place

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14
Q

left asymmetry

A

language, encoding memories

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15
Q

right asymmetry

A

nonverbal movements, facial expressions, retrieving memories

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16
Q

differences in frontal lobe function

A

performs variety of functions, damage is unlikely to produce impairment to all functions-diff funct in diff sites

17
Q

disturbances of motor function

A
  • loss of fine movements, speed, and strength-after primary motor damage, loss of corticospinal projections to motor neurons, lose speed and strength contralaterally
  • loss of movement programming-damage to premotor or dorsolateral cortex, serially ordering behavior, supplementary motor cortex-improves rapidly expect in fingers, copying movements
  • changes in voluntary gaze-damage to frontal eye fields, hard to focus on specific things
  • corollary discharge or reafference-internal neural signal that movement will occur, damage disrupts discharge, voluntary movements require command and signal
  • speech-brocas(agrammatism-inability to use verbs, words based on cues), supplementary motor cortex(mute, returns if have unilateral lesion)
18
Q

convergent thinking

A

there is only 1 answer to the question

19
Q

divergent thinking

A

there are multiple answers to the questions, frontal lobe damage-cant do it

20
Q

behavioral spontaneity

A

spontaneous speech (can’t come up with many random words), decreased verbal fluency design fluency general behaviors, L orbitofrontal region, some have difficulty with doodles

21
Q

symptoms of frontal lobe lesions

A
increased perseveration, inability to make strategy(worse when doing new thing)-, 
loss of response inhibition(wisconsin card sorting task, stroop test)-cant change responses, flexibility in behavior broken
risk taking(iowa gambling task)-appears after damage to orbitofrontal cortex, cant follow instructions
self regulation decifits-loss of autonoetic awareness
loss of associative learning-inability to select from competing responses/learn from experience 
impaired social and sexual behaviors-phineas gage
22
Q

poor temporal memory

A

animal experiments show that frontal lobe plays role in temporal memory
area 46-provide internal representation of spatial info, delayed response test
medial regions-object recognition
dorsolateral cortex plays role in monitoring self generated responses
in humans-recency memory(order in which things have occured), prefrontal cortex

23
Q

changes in sexual and social behavior

A

pseudodepression/psychopathy, orbitofrontal lesions-abnormal sex behavior loss of cells that code facial expressions, dorsolateral reduce interest in sex,

24
Q

pseudodepression

A

change from involved and outgoing to quiet and remote after frontal lobe damage, L frontal lobe, loss of initiative, interest in sex, quiet

25
Q

pseudopsychopathy

A

quiet polite strict to outspoken brash disrespectful, lesion to R frontal lobe, immature, no social graces, promiscuity

26
Q

spatial deficit in frontal lobe?

A

to understand dorsolateral function must look at relation to posterior parietal, which has role in guiding visuomotor movements in space

27
Q

frontal facial area damage symptoms

A

sensory and motor functions of face preserved after damage, pre and postcentral gyrus contralateral to lesion, in L-loss of verbal fluency, in R-loss of design fluency

28
Q

schizophrenia

A

abnormality in mesocortical dopaminergic projection, decrease in blood flow to frontal lobes and atrophy

29
Q

parkinson’s disease

A

loss of dopamine cells in the substantia nigra that project to prefrontal cortex, lack facial expressions, spatial memory, delayed response

30
Q

korsakoff’s

A

alcohol induced damage to the dorsomedial thalamus and deficiency in frontal lobe catecholamines, metabolic disorder of CNS

31
Q

drug addiction

A

impulsive behaviors, change in structurs of neurosn in orbitofrontal and medial prefrontal regions