Parasite Drugs for Midterm Flashcards

1
Q

Metronidazole

A
  • Giardia
  • Entamoeba histolytica
  • Trichomonas Vaginalis
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2
Q

Tinidazole (Tindamax), USA

A

• Giardia

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3
Q

Spiramycin

A

• Toxoplasma gondii (prophylaxis)

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4
Q

Praziquantel

A
  • CNS NOTES say for neurocysticercosis caused by taenia solium although PARASITE NOTES say this wouldn’t work and should just do for neurocysticercosis caused by taenia saginata
  • Trematodes (echinococcus in dogs): includes schistosomas
  • Clonorchis sinensis
  • Paragonimus westermani (don’t think we covered, snail is intermediate host, get from raw crab, shrimp (paste, etc.))
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5
Q

Niclosamide

A
  • Taenia solium (use for for worm not neurocysticercosis)

* (unclear about whether it’s used for Taenia saginata)

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6
Q

Corticosteroids (general)

A
  • Neurocystercicosis
  • Toxocara canis (probably to decrease swelling of ocular and visceral larva migrans. Get via dog ownership/soil transmission, geophagia, pica)
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7
Q

Triclabendazole (livertriportal triad)

A

• Fasciola hepatica (liver fluke) (young flukes damage liverget severe headache, backache, chills and fever. Adult flukes cause atrophy of portal vessels, hemorrhage and secondary pathological conditions that may be lethal)

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8
Q

Albendazole

A
  • Geohelminths
  • Ancylostoma caninum (probably to treat cutaneous larva migrans)
  • Toxocara canis (probably to treat ocular and visceral larva migrans)
  • Neurocysticercosis caused by taenia solium
  • Echinococcus granulosus and multilocularis (use albendazole for complicated cysts. Wait and watch for cysts without protoscolioses (not dangerous). Third option for treatment is PAIR (puncture, aspiration, injection, re-aspiration))
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9
Q

Mebendazole

A
  • Geohelminths (ancyclostoma duodenale, ascaris, trichuris)

* Strongyloides stercoralis (probably to treat larva currens, usually confined to trunk)

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10
Q

Thiabendazole

A
  • Strongyloides stercoralis

* Ancylostoma caninum (topical)

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11
Q

Ivermectin

A
  • Geohelminths
  • Strongyloides stercoralis (better than other drugs for it)
  • Ancylostoma caninum
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