Specific bacterial drugs Part 2 Flashcards Preview

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1

E. coli Serotype K1--Neonatal meningitis

ampicillin + 3rd generation cephalosporin

2

Invasive E. coli:

carbapenem
UTIs: fosfomycin, nitrofurantoin
Colistin (for carbapenem res. isolates

3

Typhoid Fever

Ciprofloxacin, levofloxacin
Asians: azithromycin, ceftriaxone
Critically ill: carbapenem, then de-escalate

4

Shigella

ciprofloxacin, levofloxacin (po or IV)
ceftriaxone (IV)
azithromycin (pediatric)

5

Yersinia enterocolitica

ceftriaxone

6

Yersinia pestis

gentamicin or streptomycin
PEP: doxycycline or cipfofloxacin

7

Klebsiella pneumoniae

cephalosporins or fluoroquinolones

8

Klebsiella granulomatis

doxycycline > 3 weeks

9

Cholera

rehydration therapy:
IV ringer's lactate
Oral rehydration salts

single dose doxycycline
azithromycin (kids, pregnancy)

10

C. jejunni

azithromycin

11

life threatening campylobacter (usually C. fetus)

carbapenem, aminoglycoside

12

Gram - Anaerobes

metronidazole, carbapenem, beta-lactam plus inhibitor

13

propionibacterium

benzoyl peroxide
erythromycin

14

actinomyces

surgical debridement
penicillin

15

mobiluncus
T. vaginallis

metronidazole or clindamycin

16

Lactobacilli

penicillin + aminoglycoside

17

C. diff

metronidazole or vancomycin
discontinue associated antibiotic treatment

18

Francisella tularensis

gentamicin, tobramycin (streptomycin)
alternatives: doxycycline (all tick infections)

19

Syphillis

penicillin G (IM)

20

LBRF

Tetracycline

21

TBRF

Doxycycline

22

Leptospira

IV penicillin

23

Leptospira exposure

Oral doxycycline

24

Helicobacter

PPI
sequential antibiotics: amoxicillin-->clarithroycin/levofloxacin + tinidazole

25

Pseudomonas aeruginosa

anti-pseudomonal beta-lactam + beta lactamase inhibitor + aminoglycoside

26

B. cepacia

TMP-SMX
carbapenem
fluoroquinolone

27

B. pseudomallei

IV cephalosporin/carbapenem followed by oral TMP-SMX + doxycycline

28

Moraxella

penicillin w/ beta-lactamase inhibitor

susceptible to all other antibiotics used for respiratory therapy: macrolides, fluoroquinolones, tetracyclines

29

Invasive H. influenzae

3rd gen cephalosporins

30

H. influenzae otitis media, sinusitis

ampicillin
cecphalosporin
fluoroquinolone