Research Into Klinefelters

Question 1

What did Simpson et al find?(difficulties)

Answer 1

Behavioural/language difficulties resulting from KF can be successfully treated with androgen therapy, such as testosterone supplements/counselling

Question 2

What did Swerdlow et al 2005 investigate?(mortality)

Answer 2

Mortality in men with KF between 1959 and 2003 in the UK

Question 3

What did Swerdlow et al find?(mortality)

Answer 3

461 of 3518 men had died, which is higher than similar non-KF patient

Question 4

What did Swerdlow et al find about major causes of death?(mortality)

Answer 4

That they were from cardiovascular diseases as well as diabetes

Question 5

What did DeLisi et al 2005 subject?(interviews etc)

Answer 5

11 KF participants and 11 non-KF participants to a psychiatric interview, cognitive tests and an MRI scan

Question 6

What did DeLisi et al find?

Answer 6

10 of the KF males had some form of psychiatric disturbance and generally KF sufferers had smaller frontal & temporal lobes

Question 7

What did Stockholm et al 2012 investigate?(criminal)

Answer 7

Criminal patterns in 1005 Danish men with standard KF syndrome

Question 8

What did Stockholm et al find?(criminals)

Answer 8

Men with KF had higher conviction rates for sexual abuse, burglary and arson, and lower conviction rates for traffic/drug offences than males without KF