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Flashcards in Hematology Deck (72)
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1

Blood = ______ + ______

Plasma + Cells

2

Plasma is composed of _______.

organic + inorganic substances (including proteins) dissolved in water

3

Cells in the blood include _____.

WBCs, RBCs, and platelets

4

Plasma is about _______ water.

90%

5

________ make up most of the solute weight of the plasma.

Dissolved proteins

6

Examples of proteins in plasma include _________ (3 of them).

Albumins
Globulins
Fibrinogen

7

Plasma is a _________. (Primary Function)

Transporter

8

Hematopoiesis is the _________.

Production of blood cells.

9

Hematopoiesis occurs in the ________.

Bone marrow

10

Hematopoiesis produces a ________ first, which then divides into ______ and _______ cells.

1. Pluripotent stem cell
2. Lymphoid
3. Myeloid

11

Lymphoid cells mature into ________.

Lymphocytes

12

Myeloid cells mature into _______ (3 Cells).

1. Erythrocytes
2. Leukocytes
3. Platelets

13

All blood cells originate from ________.

Pluripotent stem cells

14

What is unique about a RBC's shape? What does this increase?

They are a biconcave disc, which increases their surface area and makes them flexible

15

What is the primary function of a erythrocyte?

Oxyegn/Carbon Dioxide transporter.

16

Do erythrocytes have a nucleus or mitochondria?

No

17

Can erythrocytes preform mitosis or aerobic respiration?

No

18

What molecule does erythrocytes carrying that contributes to the pH of blood?

Carbonic anhydrase

19

What is the lifespan of an erythrocyte?

80-120 days (00 day average)

20

Platelets are _____ shaped.

Irregularly

21

The life span of a platelet is ______ days.

8-11

22

The primary functions of a platelets are to aid in _______.

Hemostasis following vascular injury, and coagulation/clot formation

23

What are the 3 requirements form RBC production?

1. Iron
2. Folic acid/Vitamin B12
3. EPO

24

What does EPO stand for?

Erythropoetin

25

Hgb is a ____ piece molecule with _____ incorporated into its structure at _____ different sites.

1. 4
2. Fe++
3. 4

26

Hgb helps RBCs carry ______.

O2

27

In tissues that are more acidic, Hgb will hold onto O2 more _______.

Loosely

28

In tissues that are more basic, Hgb will hold onto O2 more ________.

Tightly

29

Name a scenario in which Hgb would hold onto O2 loosely.

Lactic acid build up in tissues when someone is exercising

30

Name a scenario in which Hgb would hang onto O2 tightly.

In a fetus (O2 has a longer way to travel to reach the baby from the mother)