Disseminated Intravascular Coagulation (DIC) Flashcards
1
Q
what is DIC?
A
excessive and inappropriate activation of the haemostatic system (primary, secondary and fibrinolysis)
2
Q
wha causes end organ failure in DIC?
A
microvascular thrombus formation
3
Q
causes of DIC
A
anything that causes massive tissue damage and leads to activation
- sepsis
- obstetric emergencies
- malignancy
- hypovolvaemic shock
4
Q
presentation of DIC
A
clotting factor consumption
- bruising
- purpura
- generalised bleeding
5
Q
management of DIC
A
treat underlying cause
replacement therapy= platelet transfusions, plasma transfusions, fibrinogen replacement
6
Q
diagnosis of DIC
A
D-dimers
