Ionic basis of an action potential Flashcards

1
Q

How is a resting potential produced?

A

Sodium/potassium ATPase powered pump produces a high concentration of sodium extracellularly and potassium intracellularly
Slow outward leak of potassium leads to a negative intracellular potential of -70 mV
If the inside of the cell becomes less negative and reaches the threshold potential of -55 mV, an action potential is generated
Sodium channels open to allow influx of ions
This produces depolarisation
Potassium channels open to allow efflux of ions
Producing repolarisation
After a short refractory period, another action potential can be generated

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