DLA 14 Flashcards

1
Q

What are the consequences of altering a nucleotide sequence?

A

nonsense mutation
silent mutation
missense mutation

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2
Q

What is the start codon?

A

AUG

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3
Q

What are stop codons?

A

UAA

UAG

UGA

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4
Q

what are the components required for translation?

A

mRNA

ribosomes

charged tRNA

GTP

initiation factors

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5
Q

What are the three binding sites of the ribosome?

A

P site

A site

E site

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6
Q

What does the P site do?

A

holds the tRNA that carries the growing chain

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7
Q

What does the A site do?

A

holds the tRNA that carries the next AA to be added

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8
Q

What does the E site do ?

A

the exit site

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9
Q

What are the prokaryotic subunits of the ribosome?

A

50S and 30S = 70S

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10
Q

What are the eukaryotic subunits of the ribosome?

A

60S and 40S = 80 S

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11
Q

The wobble hypothesis?

A

The first two bases of the codon are traditional, but the last base is less stringent

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