continuous breeding

Question 1

what receptor does kisspeptin act on?

Answer 1

ligand for orphan gprotein coulped receptor, GPR54. increases GnRH secretion in hypothalamus.

Question 2

where is GnIH secreted

Answer 2

dorsomedial nucleus in hypothalamus

Question 3

where is CRH secreted

Answer 3

paraventricular nucleus in hypothalamus

Question 4

where is GnRH secreted

Answer 4

preoptic region in hypothalamus

Question 5

where is kisspeptin secreted

Answer 5

arcuate nucleus in hypothalamus

Question 6

what is leptin?

Answer 6

released from adipose cells, major satiety signal to hypothalamus. lackof leptin or resistance leads to excessive appetite and obesity.

Question 7

what does NPY do?

Answer 7

inhibits kisspeptin and GnRH

Question 8

what does POMC do?

Answer 8

increases GnRH and kisspeptin

Question 9

how does leptin affect POMC and NPY?

Answer 9

increases POMC but decreases NPY. THIS WILL INCREASE GnRH.

Question 10

how does leptin resistance affect breeding in humans?

Answer 10

over elevated leptin levels will have no effect of POMC and NPY and so POMC isnt activated to increase GnRH and NPY isnt supressed and will inhibit kisspeptin and GnRH. less sexual function.