Anxiety Flashcards

1
Q

Outline General Anxiety Disorder (GAD) and some disorders it includes

A

Abnormal and pathological fear and anxiety - one of a range of anxiety disorders including panic disorder, PTSD, OCD, social phobia, specific phobias, acute stress disorder, body dystrophic disorders

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2
Q

What are the psychological and physical features of GAD?

A

Psychological: worry, interrupted sleep, poor concentration, increased sensitivity to noise

Physical: sweating, dry mouth, urinary frequency, hyperventilation, dizziness, palpitations

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3
Q

Outline the DSM-IV diagnosis of GAD

A

Excessive anxiety and worry occurring more days than not, for at least 6 months about a number of events or activities

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4
Q

What are predispositions to GAD?

A

Biopsychosocial factors, social environment, perceived control

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5
Q

Define stress and what are the 4 ways it can be classed

A

Stress = feeling overwhelmed by situations, real or perceived (an inability to cope)

Affective - shock, distress, anxiety, fear
Behavioural - smoking, alcohol, social withdrawal, help seeking delay
Cognitive - poor attention, memory loss, hypervigilance
Physiological - activation of NS, cortisol production, fatigue, illness

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6
Q

Define fear and which brain areas are involved

A

Fear = acute response to an actual stressor

Involves amygdala and other limbic areas (insula cortex, PAG)

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7
Q

What are the two main ways people cope with stress?

A

Problem-focused coping: attempts to manage the aspects of the stressor, most effective when the stressor is amenable to change

Emotion-focused coping: attempts to remove or reduce the emotional distress, most effective when the stressor can’t be changed

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8
Q

What are the treatments for GAD?

A

Psychotherapy: CBT, counselling, relaxation courses, hypnotherapy, conscious avoidance

Medication: Propranolol (B-blocker for physical symptoms), SSRI (Sertraline), SNRI (Venlafaxine) or Risperidone/Amitryptiline (antipsychotic)

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9
Q

What are the 6 symptoms that anxiety/worry are associated with for a diagnosis? How many must you have?

A
3 or more out of the 6:
Restlessness
Easily fatigued
Difficulty concentrating
Irritability
Muscle tension
Sleep disturbance
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10
Q

What are 3 features of coping with anxiety?

A

Magnification - exaggerating the importance of undesired events
Overgeneralisation - drawing broad negative conclusions on the basis of a single insignificant event
Selective attention - seeing only the negative features of an event

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11
Q

What are 3 perspectives to understanding stress?

A

Stimulus
Response
Process

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12
Q

What are the 3 stages of physiological stress response?

A

Alarm - SNS, endocrine and immune systems activated
Resistance - conservation response initiated to return homeostasis
Exhaustion - depletion of physiological resources; immune failures and disease outcomes

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13
Q

What’re the physiological effects of stress in-patients vs those discharged

A

Inpatients: slower wound healing, longer stay, more staff time, more analgesia use, poor adherence to medication, more post-surgery complications

Discharged: longer recovery/return to work, more service use, less use of rehab services, increased risk of comorbidity/early mortality

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14
Q

What’s the transactional model of stress?

A
Causal chain of influence
Stimulus event (stressor) -> primary appraisal -> secondary appraisal -> response/coping -> health related outcome
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15
Q

What’re the definitions of fear, anxiety and stress?

A

Fear - acute response to an actual stressor
Anxiety - towards a perceived or potential stressor
Stress - feeling overwhelmed by situations, real or perceived

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16
Q

What CNS areas are involved in anxiety and fear?

A
Amygdala
PFC
Insula (threshold for emotions)
Limbic system areas
Association areas - frontal and parietal
17
Q

Where is the insula cortex located?

A

Behind lateral/sylvian fissure (spearing frontal and parietal lobes)

18
Q

Which brainstem region controls defence behaviours and what types of receptor dominate here?

A

PAG - opioid receptors (relevant to analgesia too as increases descending inhibition to SC)

19
Q

What mechanisms might there be in brain areas producing anxiety/stress behaviours?

A

Increased CNS activity
Increased neuronal synchrony
Changes in firing frequency, morphological changes, genetic/epigenetic changes

20
Q

What can psychotherapy do to neurones?

A
New learning
Overwrite/depress old learning
Alter brain activity frequencies
Desensitising
MRI shows altered activity
21
Q

What’s GAD-7 and how is it scored?

A

Rapid screening tool for clinical anxiety

Mild anxiety = score 5-9
Moderate = score 10-14
Severe = >15

22
Q

What are the 7 questions in GAD-7?

A

How often in the past 2 weeks…

Feeling nervous/anxious
Unable to stop worrying
Worrying about different things
Trouble relaxing
Being so restless its hard to sit still
Easily annoyed/irritable
Afraid something awful might happen